 |
CaMKII (H-300) Antibody: sc-13082 |
| Datasheet |
|
- rabbit polyclonal IgG, 200 µg/ml
- epitope corresponding to amino acids 1-300 mapping at the N-terminus of CaMKIIα of human origin
- recommended for detection of α, β, γ and δ subunits of CaMKII of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
|
|
| |
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
CaMKII Background Information
The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is a ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+and calmodulin (CaM) and has been implicated in regulation of the cell cycle and transcription. There are four CaMKII isozymes designated å, ∫, © and ∂, which may or may not be co-expressed in the same tissue type. CaMKIV is stimulated by Ca2+ and CaM but also requires phosphorylation by a CaMK for full activation. Stimulation of the T cell receptor CD3 signaling complex with an anti-CD3 monoclonal antibody leads to a 10-40 fold increase in CaMKIV activity. An additional kinase, CaMKK, functions to activate CaMKI through the specific phosphorylation of the regulatory Threonine residue at position 177.
| CaMKII (H-300) Product Citations |
See how others have used CaMKII (H-300): sc-13082 antibody and or CaMKII (H-300) antibody conjugates.
13 total citations Loading citations.
|
| |
|
|
|
CaMKII (H-300)
Click on image to enlarge
|
|
CaMKII (H-300): sc-13082. Western blot analysis of CaMKII expression in mouse brain tissue extract.
CaMKII (H-300): sc-13082. Immunoperoxidase staining of formalin fixed, paraffin-embedded mouse brain tissue showing cytoplasmic localization.
CaMKII (H-300): sc-13082. Western blot analysis of CaMKIIδ expression in non-transfected: sc-117752 (A) and human CaMKIIδ transfected: sc-115074 (B) 293T whole cell lysates and mouse brain tissue extract (C). CaMKII (H-300): sc-13082. Western blot analysis of CaMKII expression in mouse brain tissue extract
CaMKII (H-300): sc-13082. Western blot analysis of CaMKII expression in mouse brain tissue extract.
CaMKII (H-300): sc-13082. Western blot analysis of CaMKIIγ expression in non-transfected: sc-117752 (A) and human CaMKIIγ transfected: sc-170070 (B) 293T whole cell lysates. CaMKII (H-300): sc-13082. Immunofluorescence staining of methanol-fixed HeLa cells showing membrane and cytoplasmic localization.
CaMKII (H-300): sc-13082. Immunoperoxidase staining of formalin fixed, paraffin-embedded human urinary bladder tissue showing cytoplasmic staining of urothelial cells.
|
|
Download
|
|
