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PERK Antibody (H-300): sc-13073

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  • PERK Antibody (H-300) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to amino acids 21-320 mapping near the N-terminus of PERK of human origin
  • recommended for detection of PERK of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
  • See 42 citations for PERK Antibody (H-300)

New monos, 16satisfaction guaranteed

Try PERK (B-5): sc-377400, our highly recommended monoclonal alternative to PERK (H-300).

 
Full-length PERK protein sequence with immunogen highlighted:
MERAISPGLLVRALLLLLLLLGLAARTVAAGRARGLPAPTAEAAFGLGAAAAPTSATRVPAAGAVAAAEVTVEDAEALPAAAGEQEPRGPEPDDETELRPRGRSLVIISTLDGRIAALDPENHGKKQWDLDVGSGSLVSSSLSKPEVFGNKMIIPSLDGALFQWDQDRESMETVPFTVESLLESSYKFGDDVVLVGGKSLTTYGLSAYSGKVRYICSALGCRQWDSDEMEQEEDILLLQRTQKTVRAVGPRSGNEKWNFSVGHFELRYIPDMETRAGFIESTFKPNENTEESKIISDVEEQEAAIMDIVIKVSVADWKVMAFSKKGGHLEWEYQFCTPIASAWLLKDGKVIPISLFDDTSYTSNDDVLEDEEDIVEAARGATENSVYLGMYRGQLYLQSSVRISEKFPSSPKALESVTNENAIIPLPTIKWKPLIHSPSRTPVLVGSDEFDKCLSNDKFSHEEYSNGALSILQYPYDNGYYLPYYKRERNKRSTQITVRFLDNPHYNKNIRKKDPVLLLHWWKEIVATILFCIIATTFIVRRLFHPHPHRQRKESETQCQTENKYDSVSGEANDSSWNDIKNSGYISRYLTDFEPIQCLGRGGFGVVFEAKNKVDDCNYAIKRIRLPNRELAREKVMREVKALAKLEHPGIVRYFNAWLEAPPEKWQEKMDEIWLKDESTDWPLSSPSPMDAPSVKIRRMDPFATKEHIEIIAPSPQRSRSFSVGISCDQTSSSESQFSPLEFSGMDHEDISESVDAAYNLQDSCLTDCDVEDGTMDGNDEGHSFELCPSEASPYVRSRERTSSSIVFEDSGCDNASSKEEPKTNRLHIGNHCANKLTAFKPTSSKSSSEATLSISPPRPTTLSLDLTKNTTEKLQPSSPKVYLYIQMQLCRKENLKDWMNGRCTIEERERSVCLHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTMDDVVKVGDFGLVTAMDQDEEEQTVLTPMPAYARHTGQVGTKLYMSPEQIHGNSYSHKVDIFSLGLILFELLYPFSTQMERVRTLTDVRNLKFPPLFTQKYPCEYVMVQDMLSPSPMERPEAINIIENAVFEDLDFPGKTVLRQRSRSLSSSGTKHSRQSNNSHSPLPSN

See additional PERK Antibodies.

Also see chemical PERK Inhibitors for functional analysis of cellular responses to PERK.


Ordering InformationProduct CitationsGene Info
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
PERK Antibody (H-300) sc-13073 200 µg/ml $279
 CRISPR KO, HDR and Nickase Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PERK CRISPR/Cas9 KO Plasmid (h) sc-400080 20 µg $345
PERK HDR Plasmid (h) sc-400080-HDR 20 µg $385
PERK Double Nickase Plasmid (h) sc-400080-NIC 20 µg $355
PERK Double Nickase Plasmid (h2) sc-400080-NIC-2 20 µg $355
PERK CRISPR/Cas9 KO Plasmid (m) sc-420142 20 µg $345
PERK HDR Plasmid (m) sc-420142-HDR 20 µg $385
PERK Double Nickase Plasmid (m) sc-420142-NIC 20 µg $355
PERK Double Nickase Plasmid (m2) sc-420142-NIC-2 20 µg $355
 CRISPR Activation Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PERK CRISPR Activation Plasmid (h) sc-400080-ACT 20 µg $345
PERK CRISPR Activation Plasmid (h2) sc-400080-ACT-2 20 µg $345
PERK Lentiviral Activation Particles (h) sc-400080-LAC 200 µl $395
PERK Lentiviral Activation Particles (h2) sc-400080-LAC-2 200 µl $395
PERK CRISPR Activation Plasmid (m) sc-420142-ACT 20 µg $345
PERK CRISPR Activation Plasmid (m2) sc-420142-ACT-2 20 µg $345
PERK Lentiviral Activation Particles (m) sc-420142-LAC 200 µl $395
PERK Lentiviral Activation Particles (m2) sc-420142-LAC-2 200 µl $395
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PERK siRNA (h) sc-36213 10 µM $258
PERK siRNA (m) sc-36214 10 µM $258
PERK (h)-PR sc-36213-PR 10 µM, 20 µl $23
PERK (m)-PR sc-36214-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PERK shRNA Plasmid (h) sc-36213-SH 20 µg $520
PERK shRNA Plasmid (m) sc-36214-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PERK shRNA (h) Lentiviral Particles sc-36213-V 200 µl $625
PERK shRNA (m) Lentiviral Particles sc-36214-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
NIH/3T3 Whole Cell Lysate sc-2210 500 µg/200 µl $104
SK-N-SH Cell Lysate sc-2410 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human EIF2AK3 9451 2p11.2 NM_004836 Q9NZJ5
604032
Mouse Eif2ak3 13666 6 C1 Q9Z2B5
N/A
 


An interferon-inducible, RNA-dependent protein serine/threonine kinase (PKR) has been described. PKR in earlier literature is variously known as DAI, dsJ, PI kinase, p65, p67 or TIK for the mouse kinase; and p68 or p69 for the human kinase. The PKR kinase substrate is the å subunit of protein synthesis initiation factor eIF-2. Phosphorylation of eIF-2å on serine-51 results in inhibition of translation. The serine/threonine kinase catalytic domains map to the carboxy terminal half of the protein while the RNA-binding domains are located in the amino terminal region. PERK is a type I transmembrane protein located in the endoplasmic reticulum (ER) that contains a kinase domain similar to the kinase domain of PKR. PERK is activated in response to ER stress and phosphorylates eIF-2å, thus inhibiting the translation of mRNA.

PERK Antibody (H-300) Product Reviews

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PERK Antibody (H-300) Product Citations
See how others have used PERK Antibody (H-300) and or PERK Antibody (H-300) conjugates.


42 total citations
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PERK Antibody (H-300) Data
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PERK (H-300): sc-13073. Immunoperoxidase staining of formalin fixed, paraffin-embedded human thyroid gland tissue showing cytoplasmic and nuclear staining of glandular cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
PERK (H-300): sc-13073. Western blot analysis of PERK expression in NIH/3T3 whole cell lysate.
PERK (H-300): sc-13073. Immunoperoxidase staining of formalin fixed, paraffin-embedded human bronchus tissue showing cytoplasmic and nuclear staining of respiratory epithelial cells.
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