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NCoA-3 (H-270) Antibody: sc-13066 |
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- rabbit polyclonal IgG, 200 µg/ml
- epitope corresponding to amino acids 351-620 of NCoA-3 of human origin
- recommended for detection of NCoA-3 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
- TransCruz reagent for Gel Supershift and ChIP applications, sc-13066 X, 200 µg/0.1 ml
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NCoA-3 Background Information Nuclear receptors for steroids, thyroid hormones and retinoic acids are ligand-dependent transcription factors that activate transcription through specific DNA binding sites in their target genes. Several related transcriptional coactivators and corepressors have been described that work in concert with the steroid receptor family to either induce or repress transcription from hormone-responsive elements. This family includes GRIP1 (for GR interacting protein 1), also designated NCoA-2 or TIF-2; SRC-1 (for steroid receptor coactivator-1), also designated NCoA-1; and NCoA-3, also designated RAC3, ACTR, AIB-1 (for amplified in breast cancer) and p/CIP (for p300/CBP/co-integrator protein), which displays elevated expression in estrogen receptor positive ovarian and breast cancers and is required for the transcriptional activation of p300/CBP-dependent transcription factors.
| NCoA-3 (H-270) Product Citations |
See how others have used NCoA-3 (H-270): sc-13066 antibody and or NCoA-3 (H-270) antibody conjugates.
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NCoA-3 (H-270)
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NCoA-3 (H-270): sc-13066. Western blot analysis of NCoA-3 expression in MIA PaCa-2 whole cell lysate.
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