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p-TERT Antibody (Ser 1125): sc-130608

 |  Datasheet

(Based on data analysis)
  • p-TERT Antibody (Ser 1125) is a rabbit polyclonal IgG provided at 100 µg/ml
  • recommended for detection of Ser 1125 phosphorylated TERT of human origin by WB and ELISA
 

See additional TERT Antibodies.

Also see TERT Inhibitors for functional analysis of cellular responses to TERT.


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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
p-TERT Antibody (Ser 1125) sc-130608 100 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
TERT siRNA (h) sc-36641 10 µM $258
TERT (h)-PR sc-36641-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
TERT shRNA Plasmid (h) sc-36641-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
TERT shRNA (h) Lentiviral Particles sc-36641-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human TERT 7015 5p15.33 O14746
 609135
 

Telomerase is an RNA-dependent DNA polymerase that catalyzes the addition of telomeric repeat sequences to chromosome ends. In most human somatic cells, telomerase activity is undetectable, and telomeres shorten with successive cell divisions. However, telomerase activity is detectable in immortal cells and in many human tumors. Two candidate mammalian telomerase proteins have been cloned. Human TP1 (for telomerase-associated protein 1), also designated TLP1 in rat (for telomerase protein component 1), is homologous to the Tetrahymena p80 telomerase protein and has been shown to interact with mammalian telomerase RNA. Human TERT (for telomerase reverse transcriptase), also designated hEST2 (for ever shorter telomeres), is homologous to the p123 telomerase protein from Euplotes and to the yeast Est2 protein. Expression of TERT mRNA has been shown to correlate with telomerase activity in various cell lines.