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- goat polyclonal IgG, 200 µg/ml
- epitope mapping at the C-terminus of MCP-1 of human origin
- recommended for detection of MCP-1 of human origin by WB, IP, IF and ELISA
- blocking peptide, sc-1304 P
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Ordering InformationProduct Citations
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
CCL2 |
6347 |
17q12 |
NM_002982 |
P13500
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609423 |
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MCP-1 Background Information
Eotaxin and the monocyte chemotactic proteins, MCP-1–5, form a subfamily of the C-C (or ∫) chemokines, which are characterized by a set of conserved adjacent cysteines. MCPs are produced by a variety of cells, including T lymphocytes, subsequent to their activation with cytokines such as IL-1, TNFå and IFN-©. In vitro studies have shown that the MCP isoforms exhibit their chemotactic effects on different subpopulations of lymphocytes. MCP-1 is a potent basophil activator but does not affect eosinophils. MCP-1 levels are increased during infection and inflammation, which are both characterized by leukocyte infiltration. Two MCP-1 receptors, which differ in their carboxy-termini, have been identified.
| MCP-1 (C-17) Product Citations |
See how others have used MCP-1 (C-17): sc-1304 antibody and or MCP-1 (C-17) antibody conjugates.
6 total citations Loading citations.
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MCP-1 (C-17)
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Western blot analysis of human recombinant MCP-1 (A,C,E) and mouse recombinant MCP-1 (B,D,F). Antibodies tested include MCP-1 (C-17): sc-1304 (A,B), MCP-1 (M-18): sc-1784 (C,D) and MCP-1 (R-17): sc-1785 (E,F). MCP-1 (C-17): sc-1304. Western blot analysis of MCP-1 expression in non-transfected: sc-110760 (B) and human MCP-1 transfected: sc-111347 (A) 293 whole cell lysates. |
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