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p-Crk II Antibody (Ser 41): sc-130186

 |  Datasheet

(Based on data analysis)

  • p-Crk II Antibody (Ser 41) is a rabbit polyclonal IgG provided at 100 µg/ml
  • recommended for detection of Ser 41 phosphorylated Crk II of mouse, rat and human origin by WB, IP and ELISA
 

See additional Crk Antibodies including Crk, Crk I, Crk II and Crk-L.

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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
p-Crk II Antibody (Ser 41) sc-130186 100 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Crk II siRNA (h) sc-37072 10 µM $258
Crk II siRNA (m) sc-44854 10 µM $258
Crk II (h)-PR sc-37072-PR 10 µM, 20 µl $23
Crk II siRNA (m)-PR sc-44854-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Crk II shRNA Plasmid (h) sc-37072-SH 20 µg $520
Crk II shRNA Plasmid (m) sc-44854-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Crk II shRNA (h) Lentiviral Particles sc-37072-V 200 µl $625
Crk II siRNA shRNA (m) Lentiviral Particles sc-44854-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Crk II (m): 293T Lysate sc-125171 100 µg/200 µl $205
Crk II (h): 293 Lysate sc-110474 100 µg/200 µl $205
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human CRK 1398 17p13.3 P46108
 164762
Mouse Crk 12928 11 B5 NM_133656 Q64010
 N/A
 

The v-Crk oncogene product shares homologous amino acid sequences, designated SH2 (for Src homology region 2) and SH3, with many molecules involved in signal transduction. The v-Crk cellular homolog, c-Crk, is a member of a newly emerging class of genes, including Nck and GRB2/ASH, which encode proteins that consist primarily of SH2 and SH3 domains. Two distinct human c-Crk cDNAs, designated Crk I and Crk II, have been identified and shown to represent alternative splice products of c-Crk. The major c-Crk transforming activity appears associated with c-Crk I p28 expression. IGF-I receptor kinase can induce phosphorylation of Crk II at Tyr 221. Human Crk II may also be phosphorylated at Ser 41.
p-Crk II Antibody (Ser 41) Data
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sc-130186
p-Crk II (Ser 41): sc-130186. Western blot analysis of Crk II phosphorylation in non-transfected: sc-117752 (A) and mouse Crk II transfected: sc-125171 (B) 293T whole cell lysates.
sc-130186
p-Crk II (Ser 41): sc-130186. Western blot analysis of Crk II phosphorylation in non-transfected: sc-110760 (A) and human Crk II transfected: sc-110474 (B) 293 whole cell lysates.
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