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p-c-Yes Antibody (Tyr 537): sc-130182

 |  Datasheet

(Based on data analysis)

  • p-c-Yes Antibody (Tyr 537) is a rabbit polyclonal IgG provided at 100 µg/ml
  • raised against a short amino acid sequence containing phosphorylated Tyr 537 c-Yes of human origin
  • recommended for detection of Tyr 537 phosphorylated c-Yes of human origin, correspondingly phosphorylated Tyr 535 of mouse origin and correspondingly phosphorylated Tyr 536 of rat origin by WB, IP, IF, IHC(P) and ELISA
 

See additional c-Yes Antibodies.

Also see c-Yes Inhibitors for functional analysis of cellular responses to c-Yes.


Ordering InformationGene Info
Recommended Support Products:
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WB   IP   IF   IHC(P)   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
p-c-Yes Antibody (Tyr 537) sc-130182 100 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
c-Yes siRNA (h) sc-29860 10 µM $258
c-Yes siRNA (m) sc-29861 10 µM $258
c-Yes (h)-PR sc-29860-PR 10 µM, 20 µl $23
c-Yes (m)-PR sc-29861-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
c-Yes shRNA Plasmid (h) sc-29860-SH 20 µg $520
c-Yes shRNA Plasmid (m) sc-29861-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
c-Yes shRNA (h) Lentiviral Particles sc-29860-V 200 µl $625
c-Yes shRNA (m) Lentiviral Particles sc-29861-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
c-Yes (m): 293T Lysate sc-118893 100 µg/200 µl $205
NIH/3T3 Whole Cell Lysate sc-2210 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human YES1 7525 18p11.32 P07947
 164880
 

Src is the human homolog of the v-Src gene of the Rous sarcoma virus, also known as avian sarcoma virus or ASV. Src is the first proto-oncogenic non-receptor tyrosine kinase characterized in human. By virtue of common structural motifs, the Src family is composed of nine members in vertebrates, including Src, Yes, Fgr, Frk, Fyn, Lyn, Hck, Lck and Blk. Src-family kinases transduce signals that control a variety of cellular processes, including proliferation, differentiation, motility and adhesion. Src-family kinases contain an amino terminal cell membrane anchor followed by an SH3 domain and an SH2 domain involved in modular association and activation, respectively. Human c-Yes is the cellular homolog of the Yamaguchi sarcoma virus oncogene, Yes1. The human c-Yes gene maps to chromosome 18 and encodes a 543 amino acid protein. c-Src and c-Yes kinases are more than 80% homologous outside of unique amino-termini. Their respective SH3 and SH2 domains are capable of directing specificity in substrate binding. Human c-Yes is subject to autophosphorylation at Tyr 537.
p-c-Yes Antibody (Tyr 537) Data
Click on image to enlarge
sc-130182
p-c-Yes (Tyr 527): sc-130182. Immunoperoxidase staining of formalin fixed, paraffin-embedded human cancer tissue showing cytoplasmic staining.
sc-130182
p-c-Yes (Tyr 527): sc-130182. Western blot analysis of c-Yes phosphorylation in non-transfected 293T: sc-117752 (A), mouse c-Yes transfected 293T: sc-118893 (B) and NIH/3T3 (C) whole cell lysates.
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