 |
- rabbit polyclonal IgG, 200 µg/ml
- epitope corresponding to amino acids 180-282 of Fra-2 of human origin
- recommended for detection of Fra-2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
- TransCruz reagent for Gel Supershift and ChIP applications, sc-13017 X, 200 µg/0.1 ml
|
|
| |
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
| |
| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
FOSL2 |
2355 |
2p23.2 |
NM_005253 |
P15408
|
601575 |
| Mouse |
Fosl2 |
14284 |
5 B1 |
|
P47930
|
N/A |
| |
Fra-2 Background Information The Fos related gene, Fra-2, was initially molecularly cloned from chicken genomic DNA and shown to represent a new member of the immediate early gene family. The human counterpart of the chicken Fra-2 gene has since been described. Sequence alignment shows that the amino acid sequences conserved among Fra-2, c-Fos, Fra-1 and Fos B are contained in five regions. Region 2, the longest and most highly conserved region, contains the leucine zipper structure and the basic region, suggesting that like Fos, Fra-1 and Fos B, Fra-2 also forms heterodimers with c-Jun that recognize a specific DNA sequence such as the binding site for transcription factor AP-1. Such a model is further supported by the finding that the Fra-2 gene product forms a complex with c-Jun in growth-stimulated cells.
| Fra-2 (H-103) Product Citations |
See how others have used Fra-2 (H-103): sc-13017 antibody and or Fra-2 (H-103) antibody conjugates.
2 total citations Loading citations.
|
| |
|
 |
|
Fra-2 (H-103)
Click on image to enlarge
|
Fra-2 (H-103): sc-13017. Western blot analysis of Fra-2 expression in non-transfected 293T: sc-117752 (A), human Fra-2 transfected 293T: sc-176490 (B) and NTERA-2 cl.D1 (C) whole cell lysates.
Fra-2 (H-103): sc-13017. Western blot analysis of Fra-2 expression in non-transfected 293T: sc-117752 (A), human Fra-2 transfected 293T: sc-176435 (B) and MCF7 (C) whole cell lysates.
|
|
Download
|
|