BAIAP3 Background Information BAIAP3 (BAI1-associated protein 3), also known as BAP3, is a 1,187 amino acid transmembrane protein that contains two C2 domains, one MHD1 domain and one MHD2 domain. One of several members of the secretin receptor family, BAIAP3 is preferentially expressed in brain where it functions as an inhibitor of BAI-1 (brain-specific angiogenesis inhibitor I) and is thought to be involved in regulating synaptic functions. Additionally, BAIAP3 plays a role in the regulation of both tumor-associated exocytosis and oncogenic fusion and is a target of the tumor suppressor p53, suggesting that BAIAP3 is involved in cancer proliferation. Two isoforms of BAIAP3 exist due to alternative splicing events.
BAIAP3 (C-20)
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BAIAP3 (C-20): sc-130119. Immunoperoxidase staining of formalin fixed, paraffin-embedded human cancer tissue showing cytoplasmic staining.
BAIAP3 (C-20): sc-130119. Western blot analysis of BAIAP3 expression in SW-13 whole cell lysate (A) and mouse testis tissue extract (B).
