epitope mapping near the N-terminus of BTEB2 of human origin
recommended for detection of BTEB2 of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
blocking peptide, sc-12998 P
TransCruz reagent for Gel Supershift and ChIP applications, sc-12998 X, 200 µg/0.1 ml
BTEB2 Background Information Members of the C2H2 zinc finger family bind GC-rich motifs widely distributed in gene promoters, resulting in distinct activation or repression of transcriptional activities. In addition to Sp1, Sp2, Sp3, and Sp4, the basic transcription element binding proteins-1 and -2 (BTEB1 and BTEB2, respectively), belong to this family of transcriptional regulators. BTEB2 binds the GC-box of DNA and is expressed in fetal aorta. BTEB2 is a target for Egr-1. Expression of BTEB2 is activated by mitogen-activated protein kinase pathways. BTEB2 expression is induced in the neointima in response to vascular injury and is involved in phenotypic modulation of vascular smooth muscle cells in response to mitogen stimulation through Egr-1.
BTEB2 (A-16) Product Citations
See how others have used BTEB2 (A-16): sc-12998 antibody and or BTEB2 (A-16) antibody conjugates.
