Welcome to Santa Cruz Biotechnology!
SCBT Home
Home » Structural Proteins » Ezrin Antibodies » p-Ezrin Antibody (Tyr 354): sc-12942

p-Ezrin Antibody (Tyr 354): sc-12942

 |  Datasheet

(Based on data analysis)
  • p-Ezrin Antibody (Tyr 354) is a goat polyclonal IgG provided at 200 µg/ml; also available as rabbit IgG provided at 200 µg/ml, sc-12942-R
  • recommended for detection of Tyr 354 phosphorylated Ezrin of mouse and human origin by WB, IF and ELISA
  • blocking peptide, sc-12942 P
  • See 2 citations for p-Ezrin Antibody (Tyr 354)
 

See additional Ezrin Antibodies.

Ordering InformationProduct CitationsGene Info
Recommended Support Products:
(click button of application of choice)
WB   IF  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
p-Ezrin Antibody (Tyr 354) sc-12942 200 µg/ml $279
p-Ezrin (Tyr 354) P sc-12942 P
(peptide)
 100 µg/0.5 ml $61
p-Ezrin Antibody (Tyr 354)-R sc-12942-R 200 µg/ml $279
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Ramos Cell Lysate sc-2216 500 µg/200 µl $104
A-431 + EGF Whole Cell Lysate sc-2202 500 µg/200 µl $104
Ezrin (h2): 293T Lysate sc-170691 100 µg/200 µl $205
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human VIL2 7430 6q25.3 NM_003379 P15311
 123900
Mouse Ezr 22350 17 A1 P26040
 N/A
 

The microvillar core protein Ezrin is a tyrosine-phosphorylated protein found in epidermal growth factor-stimulated A-431 carcinoma cells (3). Ezrin is phosphorylated transiently to a high level on tyrosine residues 146 and 354 (1,2). One of the sites, Tyrosine 146, lies in the amino-terminal region of homology that is common to the Protein 4.1-Talin-Ezrin protein family (1,4). This tyrosine residue and its vicinal amino acids are conserved throughout the family which includes Radixin, Moesin, and the two phosphotyrosine phosphatases, PTP H1 and PTP MEG (1). Another phosphorylation site is Tyrosine 354, which is localized within the alpha-helical domain of Ezrin (1). Cytoplasmic signaling may result in activation of Ezrin in tyrosine phosphorylation and this suggests that Ezrin has qualities that might play a role in modulation of cell shape and adhesion (5).

p-Ezrin Antibody (Tyr 354) Product Citations
See how others have used p-Ezrin Antibody (Tyr 354) and or p-Ezrin Antibody (Tyr 354) conjugates.


2 total citations
Loading citations.