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p-Rac 1 Antibody (Ser 71)-R: sc-12924-R

 |  Datasheet

(Based on data analysis)

  • p-Rac 1 (Ser 71)-R Antibody is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to phosphorylated Ser 71 of Rac 1 of human origin
  • recommended for detection of Ser 71 phosphorylated Rac 1 of human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, bovine, porcine and avian
  • blocking peptide, sc-12924 P
  • See 1 citations for p-Rac 1 Antibody (Ser 71)-R
 

See additional Rac Antibodies including Rac, Rac 1, Rac 2, Rac 3 and Rac 4.

Also see Rac Inhibitors for functional analysis of cellular responses to Rac.


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Recommended Support Products:
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WB   IP   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
p-Rac 1 (Ser 71) P sc-12924 P
(peptide)
 100 µg/0.5 ml $61
p-Rac 1 (Ser 71)-R Antibody sc-12924-R 200 µg/ml $279
Lambda Phosphatase sc-200312 100000 units in 0.25 ml $462
Lambda Phosphatase sc-200312A 20000 units in 0.05 ml $116
Lambda Phosphatase sc-200312 100000 units in 0.25 ml $462
Lambda Phosphatase sc-200312A 20000 units in 0.05 ml $116
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Rac 1 siRNA (h) sc-36351 10 µM $258
Rac 1 (h)-PR sc-36351-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Rac 1 shRNA Plasmid (h) sc-36351-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Rac 1 shRNA (h) Lentiviral Particles sc-36351-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
A-431 + EGF Whole Cell Lysate sc-2202 500 µg/200 µl $104
HeLa + PMA Cell Lysate sc-2258 500 µg/200 µl $104

A large number of low molecular weight GTP-binding proteins of the Ras superfamily have been identified in eukaryotic cells; they regulate many fundamental processes such as cell growth, vesicle traffic and cytoskeletal organization. GTPase-activating proteins accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins, resulting in downregulation of their active form. Rac 1 is activated in a type I interferon (IFN) dependent manner; its function is required for downstream engagement of the p38 MAP kinase pathway. The p38 MAP kinase plays an essential role in IFN-dependent transcriptional regulation. The serine/threonine kinase Akt, of the phospho-inositide 3-kinase signal transduction pathway phosphorylates serine 71 of Rac 1.

p-Rac 1 Antibody (Ser 71)-R Product Citations
See how others have used p-Rac 1 Antibody (Ser 71)-R and or p-Rac 1 Antibody (Ser 71)-R conjugates.


1 total citations
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p-Rac 1 Antibody (Ser 71)-R Data
Click on image to enlarge
sc-12924-R
Western blot analysis of Rac-1 phosphorylation in A-431 + EGF whole cell lysate. Blots were probed with p-Rac-1 (Ser 71)-R: sc-12924-R preincubated with cognate phosphorylated (A) and unphosphorylated (B) peptide.
sc-12924-R
p-Rac 1 (Ser 71)-R: sc-12924-R. Western blot analysis of Rac 1 phosphorylation in untreated (A), PMA treated (B) and PMA and lambda protein phosphatase treated (C) HeLa whole cell lysates.
sc-12924-R
Western blot analysis of Rac 1 phosphorylation in untreated (A,C) and lambda protein phosphatase (sc-200312A) treated (B,D) HL-60 whole cell lysates. Antibodies tested include p-Rac 1 (Ser 71)-R: sc-12924-R (A,B) and Rac 1 (C-11): sc-95 (C,D).
sc-12924-R
Western blot analysis of Rac 1 phosphorylation in untreated (A,C) and lambda protein phosphatase (sc-200312A) treated (B,D) 293T whole cell lysates. Antibodies tested include p-Rac 1 (Ser 71)-R: sc-12924-R (A,B) and Rac 1 (C-11): sc-95 (C,D).
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