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p-PKA IIα reg Antibody (Ser 96): sc-12905

 |  Datasheet

(Based on data analysis)
  • p-PKA IIα reg Antibody (Ser 96) is a goat polyclonal IgG provided at 200 µg/ml; also available as rabbit IgG provided at 200 µg/ml, sc-12905-R
  • raised against a short amino acid sequence containing phosphorylated Ser 96 of PKA IIα reg of mouse origin
  • recommended for detection of Ser 96 phosphorylated PKA IIα reg of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • blocking peptide, sc-12905 P
  • See 5 citations for p-PKA IIα reg Antibody (Ser 96)
 

See additional PKA Antibodies including PKA, PKA alpha cat, PKA beta cat, PKA gamma cat, PKA I alpha reg, PKA I beta reg, PKA II alpha reg, PKA II beta reg and PKA Phosphopeptide Substrate.

Also see PKA Inhibitors, PKA Activators or PKA Substrates for functional analysis of cellular responses to PKA.


Ordering InformationProduct CitationsGene Info
Recommended Support Products:
(click button of application of choice)
WB   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
p-PKA IIα reg Antibody (Ser 96) sc-12905 200 µg/ml $279
p-PKA IIα reg (Ser 96) P sc-12905 P
(peptide)
 100 µg/0.5 ml $61
p-PKA IIα reg Antibody (Ser 96)-R sc-12905-R 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
PKA IIα reg siRNA (h) sc-39164 10 µM $258
PKA IIα reg siRNA (m) sc-39165 10 µM $258
PKA IIα reg (h)-PR sc-39164-PR 10 µM, 20 µl $23
PKA IIα reg (m)-PR sc-39165-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
PKA IIα reg shRNA Plasmid (h) sc-39164-SH 20 µg $520
PKA IIα reg shRNA Plasmid (m) sc-39165-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
PKA IIα reg shRNA (h) Lentiviral Particles sc-39164-V 200 µl $625
PKA IIα reg shRNA (m) Lentiviral Particles sc-39165-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
mouse brain extract sc-2253 500 µg/200 µl $104
NIH/3T3 Whole Cell Lysate sc-2210 500 µg/200 µl $104
KNRK Whole Cell Lysate sc-2214 500 µg/200 µl $104
Mv 1 Lu Cell Lysate sc-3810 500 µg/200 µl $104
MDCK Cell Lysate sc-2252 500 µg/200 µl $104
MCF7 Whole Cell Lysate sc-2206 500 µg/200 µl $104
PC-3 Cell Lysate sc-2220 500 µg/200 µl $104
A549 Cell Lysate sc-2413 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human PRKAR2A 5576 3p21.31 NM_004157 P13861
 176910
Mouse Prkar2a 19087 9 F2 P12367
 N/A
 

The second messenger cyclic AMP (cAMP) mediates diverse cellular responses to external signals such as proliferation, ion transport, regulation of metabolism and gene transcription by activation of the cAMP-dependent protein kinase (cAPK or PKA). Activation of PKA occurs when cAMP binds to the two regulatory subunits of the tetrameric PKA holoenzyme, resulting in release of active catalytic subunits. Activation of transcription upon elevation of cAMP levels results from translocation of PKA to the nucleus, where it phosphorylates the transcription factor cAMP response element binding protein (CREB) on Serine 133, which in turn leads to TFIIB binding to TATA-box-binding protein TBP1, thus linking phospho-CREB to the Pol II transcription initiation complex. Mouse Serine 96 (designated Ser 99 in human) is a putative phosphorylation site on the PKA IIå regulatory subunit.

p-PKA IIα reg Antibody (Ser 96) Product Citations
See how others have used p-PKA IIα reg Antibody (Ser 96) and or p-PKA IIα reg Antibody (Ser 96) conjugates.


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