Welcome to Santa Cruz Biotechnology!
SCBT Home
Home » Kinases and Phosphatases » PKC Antibodies » p-PKC ζ Antibody (Thr 410)-R: sc-12894-R

p-PKC ζ Antibody (Thr 410)-R: sc-12894-R

 |  Datasheet

(Based on data analysis)

  • p-PKC ζ (Thr 410)-R Antibody is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to phosphorylated Thr 410 of nPKC ζ of human origin
  • reactive with Thr 410 phosphorylated PKC ζ and correspondingly phosphorylated PKC ι by mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • blocking peptide, sc-12894 P
  • See 5 citations for p-PKC ζ Antibody (Thr 410)-R
 

See additional PKC Antibodies including PKC, PKC alpha, PKC beta, PKC delta, PKC epsilon, PKC eta, PKC gamma, PKC iota, PKC lambda, PKC mu, PKC nu, PKC theta, PKC zeta and Pkc1.

Also see PKC zeta Inhibitors, PKC zeta Activators or PKC zeta Substrates for functional analysis of cellular responses to PKC zeta and PKC zeta.


Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
p-PKC ζ (Thr 410) P sc-12894 P
(peptide)
 100 µg/0.5 ml $61
p-PKC ζ (Thr 410)-R Antibody sc-12894-R 200 µg/ml $279
Lambda Phosphatase sc-200312 100000 units in 0.25 ml $462
Lambda Phosphatase sc-200312A 20000 units in 0.05 ml $116
Lambda Phosphatase sc-200312 100000 units in 0.25 ml $462
Lambda Phosphatase sc-200312A 20000 units in 0.05 ml $116
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
PKC ζ siRNA (h) sc-29451 10 µM $258
PKC ζ siRNA (m) sc-36254 10 µM $258
PKC ζ (h)-PR sc-29451-PR 10 µM, 20 µl $23
PKC ζ (m)-PR sc-36254-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
PKC ζ shRNA Plasmid (h) sc-29451-SH 20 µg $520
PKC ζ shRNA Plasmid (m) sc-36254-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
PKC ζ shRNA (h) Lentiviral Particles sc-29451-V 200 µl $625
PKC ζ shRNA (m) Lentiviral Particles sc-36254-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
NIH/3T3 Whole Cell Lysate sc-2210 500 µg/200 µl $104

Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions, including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes, including conventional (c) PKC isoforms (å, ∫I, ∫II and ©) and novel (n) PKC isoforms (∂, é , Ω, h and †). Upon phosphorylation on Thr-507, PKC ∂ is activated, where it can inhibit the functionality of specific substrates, such as Jak2 and Stat3. PKC ∂ phosphorylates and associates with Stat3 on Ser-727 following induction by IL-6 to negatively regulate the DNA binding and transcriptional activity of Stat3. Phosphorylation of PKC Ω is induced by PDK1.

p-PKC ζ Antibody (Thr 410)-R Product Citations
See how others have used p-PKC ζ Antibody (Thr 410)-R and or p-PKC ζ Antibody (Thr 410)-R conjugates.


5 total citations
Loading citations.
 
p-PKC ζ Antibody (Thr 410)-R Data
Click on image to enlarge
sc-12894-R
p-PKC ζ (Thr 410)-R: sc-12894-R. Western blot analysis of PKC ζ phosphorylation in untreated (A), PMA treated (B) and PMA and lambda protein phosphatase treated (C) HeLa whole cell lysates.
sc-12894-R
p-PKC ζ (Thr 410)-R: sc-12894-R. Western blot analysis of PKC ζ phosphorylation in untreated (A), PMA treated (B) and PMA and lambda protein phosphatase treated (C) NIH/3T3 whole cell lysates.
sc-12894-R
Western blot analysis of PKC ζ phosphorylation in non-transfected: sc-117752 (A,D), untreated human PKC ζ transfected: sc-170980 (B,E) and lambda protein phosphatase treated human PKC ζ transfected: sc-170980 (C,F) 293T whole cell lysates. Antibodies tested include p-PKC ζ (Thr 410)-R: sc-12894-R (A,B,C) and PKC ζ (H-1): sc-17781 (D,E,F).
sc-12894-R
Western blot analysis of PKC ζ phosphorylation in untreated (A,D), PMA treated (B,E) and PMA and lambda protein phosphatase treated (C,F) HeLa whole cell lysates. Antibodies tested include p-PKC ζ (Thr 410)-R: sc-12894-R (A,B,C) and PKC ζ (H-1): sc-17781 (D,E,F).
sc-12894-R
Western blot analysis of PKC ζ phosphorylation in non-transfected: sc-117752 (A,D), untreated human PKC ζ transfected: sc-170980 (B,E) and lambda protein phosphatase (sc-200312A) treated human PKC ζ transfected: sc-170980 (C,F) 293T whole cell lysates. Antibodies tested include p-PKC ζ (Thr 410)-R: sc-12894-R (A,B,C) and PKC ζ (H-1): sc-17781 (D,E,F).
Download
Datasheets
Get Adobe Acrobat Reader