santa cruz biotechnology, inc.

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- Armenian hamster monoclonal IgG, 200 µg/ml
- raised against purified recombinant mouse interferon-γ
- recommended for detection of precursor and mature IFN-γ of mouse origin by functional assay
- also provided azide-free for neutralization, sc-12743 L, 200 µg/0.1 ml
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Ordering Information
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Mouse |
Ifng |
15978 |
10 D2 |
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P01580
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N/A |
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IFN-γ Background Information Interferon (IFN)-© is an antiviral and antiparasitic agent produced by CD4+/CD8+ lymphocytes and natural killer cells that undergo activation by antigens, mitogens or alloantigens. IFN-© production modulates T cell growth and differentiation and inhibits the growth of B cells. Synthesis of IFN-© is inducible by IL-2 , FGF and EGF. The active form of IFN-© is a homodimer with each subunit containing six helices. The dimeric structure of human IFN-© is stabilized by non-covalent interactions through the interface of the helices. IFN-© translated precursor is 166 amino acids, including the 23 amino acid secretory sequence. Multiple forms exist due to variable glycosylation and under non-denaturing conditions due to dimers and tetramers. |
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