Cet anticorps polyclonal n'est plus commercialisé. Voir l'anticorps monoclonal Smac (C-10) que nous recommandons (données d'échantillonnage indiquées).
Anticorps Smac (V-17): sc-12683
- L'anticorps Smac V-17 est un polyclonal IgG de chèvre fourni en 200 µg/ml
- épitope situé près de la région N-terminus de mature Smac d'origine human
- Anticorps polyclonal arrêté
ACCÈS RAPIDE AUX LIENS
Description
The activation of caspases is a key regulatory step in apoptosis. Once cytochrome c is released from the mitochondria into the cytosol, it binds Apaf-1 to form an oligomeric cytochrome c/Apaf-1 complex, which induces caspase activation. Inhibitors of Apoptosis Proteins (IAPs), are a family of proteins that regulate the cytochrome c/Apaf-1 caspase activating pathway. Like cytochrome c, Smac (for second mitochondria-derived activator of caspase, also designated DIABLO in mouse for direct IAP binding protein with low PI) promotes caspase activation in the cytochrome c/Apaf-1/caspase-9 pathway by binding IAPs and preventing them from inhibiting caspases. In healthy cells, Smac is a mitochondrial protein, but when cells undergo apoptosis, Smac is released into the cytosol.
Informations pour la commande
Smac (C-10): sc-393118 [ Monoclonal recommandé en remplacement de Smac (V-17) ]
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Smac (C-10) | sc-393118 | 200 µg/ml | $322.00 | |||
Smac (C-10): m-IgG Fc BP-HRP Kit | sc-530360 | 200 µg Ab; 10 µg BP | $361.00 | |||
Smac (C-10): m-IgGκ BP-HRP Kit | sc-523812 | 200 µg Ab, 40 µg BP | $361.00 | |||
Smac (C-10): m-IgG1 BP-HRP Kit | sc-544012 | 200 µg Ab; 20 µg BP | $361.00 | |||
Anticorps Smac (C-10) AC | sc-393118 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Anticorps Smac (C-10) HRP | sc-393118 HRP | 200 µg/ml | $322.00 | |||
Anticorps Smac (C-10) FITC | sc-393118 FITC | 200 µg/ml | $336.00 | |||
Anticorps Smac (C-10) PE | sc-393118 PE | 200 µg/ml | $349.00 | |||
Anticorps Smac (C-10) Alexa Fluor® 488 | sc-393118 AF488 | 200 µg/ml | $364.00 | |||
Anticorps Smac (C-10) Alexa Fluor® 546 | sc-393118 AF546 | 200 µg/ml | $364.00 | |||
Anticorps Smac (C-10) Alexa Fluor® 594 | sc-393118 AF594 | 200 µg/ml | $364.00 | |||
Anticorps Smac (C-10) Alexa Fluor® 647 | sc-393118 AF647 | 200 µg/ml | $364.00 | |||
Anticorps Smac (C-10) Alexa Fluor® 680 | sc-393118 AF680 | 200 µg/ml | $364.00 | |||
Anticorps Smac (C-10) Alexa Fluor® 790 | sc-393118 AF790 | 200 µg/ml | $364.00 |