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home » Homeodomain Proteins » TTF Antibody / TTF Antibodies » TTF-1 (G-17): sc-12524

TTF-1 (G-17) Antibody: sc-12524

  |  Datasheet
  • goat polyclonal IgG, 200 µg/ml
  • epitope mapping near the N-terminus of TTF-1 of human origin
  • recommended for detection of TTF-1 of mouse, rat and human origin by ELISA; also reactive with additional species, including bovine and porcine
  • blocking peptide, sc-12524 P
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-12524 X, 200 µg/0.1 ml
 
Additional TTF Antibodies ...
 
Ordering Information
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human NKX2-1 7080 14q13.3 NM_003317 P43699
 610978
Mouse Nkx2-1 21869 12 C1 P50220
 N/A
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
TTF-1 (G-17) sc-12524 200 µg/ml $279
TTF-1 (G-17) P sc-12524 P
(peptide)
 100 µg/0.5 ml $61
TTF-1 (G-17) X sc-12524 X 200 µg/0.1 ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
TTF-1 siRNA (h) sc-36756 10 µM $258
TTF-1 siRNA (m) sc-36757 10 µM $258
TTF-1 (h)-PR sc-36756-PR 10 µM $23
TTF-1 (m)-PR sc-36757-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
TTF-1 shRNA Plasmid (h) sc-36756-SH 20 µg $520
TTF-1 shRNA Plasmid (m) sc-36757-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
TTF-1 shRNA (h) Lentiviral Particles sc-36756-V 200 µl $625
TTF-1 shRNA (m) Lentiviral Particles sc-36757-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
A549 Cell Lysate sc-2413 500 µg/200 µl $104
KNRK Whole Cell Lysate sc-2214 500 µg/200 µl $104

TTF-1 Background Information
TTF-1 (thyroid transcription factor-1, BCH, BHC, NK-2, Nkx2.1, Nkx2A, TEBP, TTF1) is a member of the Nkx2 family of homeodomain-containing transcription factors and regulates the transcriptional activity of thyroid-specific genes. TTF-1 influences organogenisis and the maintenance of the differentiated phenotypes of various tissues including thyroid, lung and brain. TTF-1, which is present in the epithelium of the lung, regulates transcription of the surfactant proteins (SP) A, B and C and is essential for lung morphogenesis. In the thyroid, TTF-1 elevates the expression of thyroid specific markers, thyroglobulin, thyroperoxidase and thyrotropin receptors. TTF-1 interacts with SRC-1 and CBP in vitro.