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- goat polyclonal IgG, 200 µg/ml
- epitope mapping near the N-terminus of Brg-1 of human origin
- recommended for detection of Brg-1 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine, bovine, porcine and avian
- blocking peptide, sc-12520 P
- TransCruz reagent for Gel Supershift and ChIP applications, sc-12520 X, 200 µg/0.1 ml
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Ordering InformationProduct Citations
Recommended Support Products:
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
SMARCA4 |
6597 |
19p13.2 |
NM_003072 |
P51532
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603254 |
| Mouse |
Smarca4 |
20586 |
9 A3 |
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NP_035547
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N/A |
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Brg-1 Background Information
The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2å) and Brg-1 (also designated SNF2ß) are the ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI-SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits are thought to play regulatory roles. hSNF2L and hSNF2H both appear to be homologs of Drosophila ISWI, a Brm related ATPase that is present in chromatin remodeling complexes other than SWI/SNF, including the NURF (nucleosome remodeling factor).
| Brg-1 (P-18) Product Citations |
See how others have used Brg-1 (P-18): sc-12520 antibody and or Brg-1 (P-18) antibody conjugates.
2 total citations Loading citations.
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Brg-1 (P-18)
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Brg-1 (P-18): sc-12520. Western blot analysis of Brg-1 expression in K-562 (A) and HeLa (B) nuclear extracts.
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