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home » Kinases and Phosphatases » Rsk Antibody / Rsk Antibodies » p-Rsk (Ser 227): sc-12445

p-Rsk (Ser 227) Antibody: sc-12445

  |  Datasheet
  • goat polyclonal IgG, 200 µg/ml; also available as rabbit IgG, 200 µg/ml, sc-12445-R
  • epitope corresponding to a short amino acid sequence containing phosphorylated Ser 227 of Rsk-2 of human origin
  • broadly reactive with Ser 227 phosphorylated Rsk family proteins of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • blocking peptide, sc-12445 P
 
Additional Rsk Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human RPS6KA3 6197 Xp22.12 NM_004586 P51812
 303600
Mouse Rps6ka1 20111 4 D3 P18653
 N/A
Mouse Rps6ka2 20112 17 A1 Q9WUT3
 N/A
Mouse Rps6ka6 67071 X E1 Q7TPS0
 N/A
Mouse Rps6ka3 110651 X F4 P18654
 N/A
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
p-Rsk (Ser 227) sc-12445 200 µg/ml $279
p-Rsk (Ser 227) P sc-12445 P
(peptide)
 100 µg/0.5 ml $61
p-Rsk (Ser 227)-R sc-12445-R 200 µg/ml $279
Lambda Phosphatase sc-200312 100,000 units $462
Lambda Phosphatase sc-200312A 20,000 units $116
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HeLa + PMA Cell Lysate sc-2258 500 µg/200 µl $104

Rsk Background Information
The family of ribosomal S6 kinases (Rsks), designated Rsk-1 (or MAPKAP kinase-1), Rsk-2 and Rsk-3, are intracellular serine/threonine kinases that are important signaling intermediates in response to a broad range of ligand activated receptor tyrosine kinases. A unique feature common to the members of the Rsk family is that each possesses two non-identical complete kinase catalytic domains. An additional Rsk protein, Rsk-4, shows a high level of homology to the three previously isolated members of the human Rsk family. Rsk-4 is most abundantly expressed in brain and kidney and plays a role in normal neuronal development. The family of ribosomal S6 kinases includes p70 S6 kinase and p70 S6 kinase b, which are thought to have similar regulatory functions. MSK1 (also designated RLPK) is a novel Rsk-related protein, which, like the p90 Rsk family members, contains two non-identical complete kinase catalytic domains.

p-Rsk (Ser 227) Product Citations
See how others have used p-Rsk (Ser 227): sc-12445 antibody and or p-Rsk (Ser 227) antibody conjugates.


6 total citations
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p-Rsk (Ser 227)
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sc-12445
p-Rsk (Ser 227)-R: sc-12445-R. Western blot analysis of Rsk phosphorylation in untreated (A), PMA treated (B) and PMA and lambda protein phosphatase treated (C) HeLa whole cell lysates.
sc-12445
Western blot analysis of Rsk phosphorylation in untreated (A,C) and lambda protein phosphatase treated (B,D) HeLa whole cell lysates. Antibodies tested include p-Rsk (Ser 227)-R: sc-12445-R (A,B) and Rsk-1 (C-21): sc-231 (C,D).
sc-12445
Western blot analysis of Rsk phosphorylation in untreated (A,D), serum-starved, PMA-treated (B,E), and serum-starved, PMA and lambda protein phosphatase (sc-200312A) treated (C,F) HeLa whole cell lysates. Antibodies tested include p-Rsk (Ser 227)-R: sc-12445-R (A,B,C) and Rsk-1 (C-21): sc-231 (D,E,F).
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