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BI-1 Antibody (G-19): sc-12394

 |  Datasheet

(Based on data analysis)
  • BI-1 Antibody (G-19) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping near the C-terminus of BI-1 of human origin
  • recommended for detection of BI-1 of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
  • blocking peptide, sc-12394 P
 

See additional BI-1 Antibodies.

Ordering InformationGene Info
Recommended Support Products:
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WB   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
BI-1 Antibody (G-19) sc-12394 200 µg/ml $279
BI-1 (G-19) P sc-12394 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
BI-1 siRNA (h) sc-37298 10 µM $258
BI-1 siRNA (m) sc-37299 10 µM $258
BI-1 (h)-PR sc-37298-PR 10 µM, 20 µl $23
BI-1 (m)-PR sc-37299-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
BI-1 shRNA Plasmid (h) sc-37298-SH 20 µg $520
BI-1 shRNA Plasmid (m) sc-37299-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
BI-1 shRNA (h) Lentiviral Particles sc-37298-V 200 µl $625
BI-1 shRNA (m) Lentiviral Particles sc-37299-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human TEGT 7009 12q13.13 NM_003217 P55061
 600748
Mouse Tegt 110213 15 F1 Q9D2C7
 N/A
 

BI-1 (Bax inhibitor 1), also designated testis enhanced gene transcript (TEGT), is a regulator of cell death pathways controlled by Bcl-2 and Bax. BI-1 is an integral membrane protein containing six membrane-spanning segments and is predominantly localized to intracellular membranes, similar to Bcl-2 family proteins. The human protein contains 237 amino acids. BI-1 can interact with Bcl-2 and Bcl-XL. When overexpressed in mammalian cells, BI-1 suppresses apoptosis induced by Bax, etoposide, staurosporine and growth factor deprivation. BI-1 antisense induces apoptosis.