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home » Signaling Intermediates » HSP Antibody / HSP Antibodies » p-HSP 27 (Ser 15): sc-12359

p-HSP 27 (Ser 15) Antibody: sc-12359

  |  Datasheet
  • goat polyclonal IgG, 200 µg/ml; also available as rabbit IgG, 200 µg/ml, sc-12359-R
  • recommended for detection of Ser 15 phosphorylated HSP 27 of human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
  • blocking peptide, sc-12359 P
 
Additional HSP Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human HSPB1 3315 7q11.23 NM_001540 P04792
 608634
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
p-HSP 27 (Ser 15) sc-12359 200 µg/ml $279
p-HSP 27 (Ser 15) P sc-12359 P
(peptide)
 100 µg/0.5 ml $61
p-HSP 27 (Ser 15)-R sc-12359-R 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HSP 27 siRNA (h) sc-29350 10 µM $258
HSP 27 siRNA (h2) sc-44264 10 µM $258
HSP 27 siRNA (m) sc-35598 10 µM $258
HSP 27 (h)-PR sc-29350-PR 10 µM $23
HSP 27 (h2)-PR sc-44264-PR 10 µM $23
HSP 27 (m)-PR sc-35598-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HSP 27 shRNA Plasmid (h) sc-29350-SH 20 µg $520
HSP 27 shRNA Plasmid (h2) sc-44264-SH 20 µg $520
HSP 27 shRNA Plasmid (m) sc-35598-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HSP 27 shRNA (h) Lentiviral Particles sc-29350-V 200 µl $625
HSP 27 shRNA (h2) Lentiviral Particles sc-44264-V 200 µl $625
HSP 27 shRNA (m) Lentiviral Particles sc-35598-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HeLa + heat shock Cell Lysate sc-2272 500 µg/200 µl $104
HeLa + UV Cell Lysate sc-2221 500 µg/200 µl $104
HSP 27 (m): 293T Lysate sc-120910 100µg/200µl $205

HSP 27 Background Information
HSP 27 is a constitutively expressed cytoplasmic protein that co-localizes to the nucleus upon stress-induced insult. Heat shock, cytokines and hormones are among the factors that stimulate the synthesis of HSP 27. The intracellular concentration of the mammalian heat shock protein, HSP 27, increases several-fold after heat shock and other metabolic stresses, and is closely associated with the acquisition of thermotolerance. MAP kinase-activated protein kinase-2 phosphorylates HSP 27 on Serine residues Ser 15, Ser 78 and Ser 82, which are phosphorylated in vivo in response to growth factors and heat shock. Ser 15, Ser 78 and Ser 82 occur in the sequence motif RXXS, which is recognized by ribosomal protein S6 kinase II.

p-HSP 27 (Ser 15) Product Citations
See how others have used p-HSP 27 (Ser 15): sc-12359 antibody and or p-HSP 27 (Ser 15) antibody conjugates.


4 total citations
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p-HSP 27 (Ser 15)
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sc-12359
p-HSP 27 (Ser 15)-R: sc-12359-R. Western blot analysis of HSP 27 phosphorylation in non-transfected: sc-117752 (A) and human HSP 27 transfected: sc-174710 (B) 293T whole cell lysates.
sc-12359
p-HSP 27 (Ser 15)-R: sc-12359-R. Western blot analysis of HSP 27 phosphorylation in non-transfected: sc-117752 (A) and human HSP 27 transfected: sc-174711 (B) 293T whole cell lysates.
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