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home » Transcription Regulators » NAB Antibody / NAB Antibodies » NAB2 (C-16): sc-12153

NAB2 (C-16) Antibody: sc-12153

  |  Datasheet
  • goat polyclonal IgG, 200 µg/ml
  • epitope mapping at the C-terminus of NAB2 of human origin
  • recommended for detection of NAB2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
  • blocking peptide, sc-12153 P
 
Additional NAB Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human NAB2 4665 12q13.3 NM_005967 Q15742
 n/a
Mouse Nab2 17937 10 D3 Q61127
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
NAB2 (C-16) sc-12153 200 µg/ml $279
NAB2 (C-16) P sc-12153 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
NAB2 siRNA (h) sc-36014 10 µM $258
NAB2 siRNA (m) sc-36015 10 µM $258
NAB2 (h)-PR sc-36014-PR 10 µM $23
NAB2 (m)-PR sc-36015-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
NAB2 shRNA Plasmid (h) sc-36014-SH 20 µg $520
NAB2 shRNA Plasmid (m) sc-36015-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
NAB2 shRNA (h) Lentiviral Particles sc-36014-V 200 µl $625
NAB2 shRNA (m) Lentiviral Particles sc-36015-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
K-562 + PMA nuclear extract sc-2131 1000 µg $143
K-562 Whole Cell Lysate sc-2203 500 µg/200 µl $104

NAB2 Background Information
Transcriptional control is in part regulated by interactions between DNA-bound transcription factors, such as Egr-1/NGFI-A, and coregulatory proteins, such as NAB (for NGFI-A-binding proteins). The evolutionarily conserved NAB proteins, NAB1 and NAB2 are corepressors of EGF-1/NGFI-A. Both NAB1 and NAB2 contain an amino terminal NAB conserved domain 1 (NCB1), which is required for binding NGFI-A, and a carboxy terminal NCD2 domain, which is responsible for the repressor function of NAB proteins. NAB2 is principally localized in the nucleus and may play a role in the downregulation of NGFI-A activity as well as in controlling fundamental processes such as cell division, differentiation and apoptosis. NAB2 localizes to chromosome 12q13.3-14.1, a region that is rearranged in several solid tumors, lipomas, and liposarcomas.

NAB2 (C-16) Product Citations
See how others have used NAB2 (C-16): sc-12153 antibody and or NAB2 (C-16) antibody conjugates.


2 total citations
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NAB2 (C-16)
Click on image to enlarge
sc-12153
NAB2 (C-16): sc-12153. Western blot analysis of NAB2 expression in non-transfected: sc-117752 (A) and human NAB2 transfected: sc-117107 (B) 293T whole cell lysates.
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