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FXR Antibody (Q-20): sc-1205

 |  Datasheet

(Based on data analysis)

  • FXR Antibody (Q-20) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping near the C-terminus of FXR of human origin
  • recommended for detection of FXR of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • blocking peptide, sc-1205 P
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-1205 X, 200 µg/0.1 ml
  • See 1 citations for FXR Antibody (Q-20)
 

See additional FXR Antibodies including FXR and FXR beta.

Also see FXR Activators for functional analysis of cellular responses to FXR.


Ordering InformationProduct CitationsGene Info
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   Gel Shift   ChIP   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
FXR Antibody (Q-20) sc-1205 200 µg/ml $279
FXR (Q-20) P sc-1205 P
(peptide)
 100 µg/0.5 ml $61
FXR Antibody (Q-20) X sc-1205 X 200 µg/0.1 ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
FXR siRNA (h) sc-38848 10 µM $258
FXR siRNA (m) sc-155894 10 µM $258
FXR siRNA (r) sc-108079 10 µM $258
FXR (h)-PR sc-38848-PR 10 µM, 20 µl $23
FXR (m)-PR sc-155894-PR 10 µM, 20 µl $23
FXR (r)-PR sc-108079-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
FXR shRNA Plasmid (h) sc-38848-SH 20 µg $520
FXR shRNA Plasmid (m) sc-155894-SH 20 µg $520
FXR shRNA Plasmid (r) sc-108079-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
FXR shRNA (h) Lentiviral Particles sc-38848-V 200 µl $625
FXR shRNA (m) Lentiviral Particles sc-155894-V 200 µl $625
FXR shRNA (r) Lentiviral Particles sc-108079-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
HeLa nuclear extract sc-2120 250 µg/0.05 ml $143
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human NR1H4 9971 12q23.1 NM_005123 Q96RI1
 603826
Mouse Nr1h4 20186 10 C2 Q60641
 N/A
 

The steroid receptor superfamily acts through direct association with DNA sequences known as hormone response elements (HREs) and binds DNA as either homo- or heterodimers. The promiscuous mediator of heterodimerization, RXR, is the receptor for 9-cis retinoic acid, and dimerizes with VDR, TR, PPAR, and several novel receptors including LXR (also referred to as RLD-1) and FXR. FXR and LXR fall into a category of proteins termed “orphan receptors” because of their lack of a defined function, and in the case of LXR, the lack of a defined ligand. FXR has been shown to bind a class of lipid molecules called farnesoids. LXR/RXR heterodimers have highest affinity for DR-4 DNA elements while FXR/RXR heterodimers bind IR-1 elements. Both LXR/RXR and FXR/RXR heterodimers retain their responsiveness to 9-cis retinoic acid.

FXR Antibody (Q-20) Product Citations
See how others have used FXR Antibody (Q-20) and or FXR Antibody (Q-20) conjugates.


1 total citations
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FXR Antibody (Q-20) Data
Click on image to enlarge
sc-1205
FXR (Q-20): sc-1205. Western blot analysis of FXR expression in HeLa nuclear extract.
sc-1205
FXR (Q-20): sc-1205. Western blot analysis of FXR expression in HeLa (A) and BJAB (B) whole cell lysates and HeLa nuclear extract (C).
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