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Integrin αX Antibody (3.9): sc-1185

 |  Datasheet

(Based on data analysis)
  • Integrin αX Antibody (3.9) is a mouse monoclonal IgG1 provided at 200 µg/ml
  • raised against human monocytes
  • recommended for detection of Integrin αX of human origin by IP, IF and FCM
  • fluorescein (sc-1185 FITC), phycoerythrin (sc-1185 PE), PerCP (sc-1185 PerCP) and PerCP-Cy5.5 (sc-1185 PCPC5) conjugates for FCM, 100 tests
  • Alexa Fluor® 488 (sc-1185 AF488) and Alexa Fluor® 647 (sc-1185 AF647) conjugates for FCM or immunofluorescence; 100 µg/2 ml
  • See 1 citations for Integrin αX Antibody (3.9)
 

See additional Integrin Antibodies including Integrin, Integrin alpha 1, Integrin alpha D, Integrin alpha E, Integrin alpha IIb, Integrin alpha IIIa, Integrin alpha IIIb, Integrin alpha L, Integrin alpha M, Integrin alpha V, Integrin alpha VIa, Integrin alpha VIb, Integrin alpha X, Integrin beta 1, Integrin beta Id, Integrin beta L1, Integrin alpha 2, Integrin beta 2, Integrin alpha 3, Integrin beta 3, Integrin alpha 4, Integrin beta 4, Integrin alpha 5, Integrin beta 5, Integrin alpha 6, Integrin beta 6, Integrin alpha 7, Integrin beta 7, Integrin alpha 8, Integrin beta 8, Integrin alpha 9, Integrin alpha 10 and Integrin alpha 11.

Also see Integrin Inhibitors for functional analysis of cellular responses to Integrin.


Ordering InformationProduct CitationsGene Info
Recommended Support Products:
(click button of application of choice)
IP   IF   FCM   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
Integrin αX Antibody (3.9) sc-1185 200 µg/ml $279
Integrin αX Antibody (3.9) Alexa Fluor® 488 sc-1185 AF488 100 µg/2 ml $314
Integrin αX Antibody (3.9) Alexa Fluor® 647 sc-1185 AF647 100 µg/2 ml $314
Integrin αX Antibody (3.9) FITC sc-1185 FITC 100 tests in 2 ml $292
Integrin αX Antibody (3.9) PCPC5 sc-1185 PCPC5 100 tests in 2 ml $310
Integrin αX Antibody (3.9) PE sc-1185 PE 100 tests in 2 ml $303
Integrin αX Antibody (3.9) PerCP sc-1185 PerCP 100 tests in 2 ml $310
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Integrin αX siRNA (h) sc-35695 10 µM $258
Integrin αX (h)-PR sc-35695-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Integrin αX shRNA Plasmid (h) sc-35695-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Integrin αX shRNA (h) Lentiviral Particles sc-35695-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Integrin αX (h4): 293T Lysate sc-158645 100 µg/200 µl $205
HL-60 + PMA Cell Lysate sc-24705 500 µg/200 µl $104
THP-1 Cell Lysate sc-2238 500 µg/200 µl $104
HL-60 Whole Cell Lysate sc-2209 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human ITGAX 3687 16p11.2 NM_000887 P20702
 151510
 

Integrin åX (CD11C, leukocyte surface antigen p150,95, CR4, Axb2) is a type 1 transmembrane protein that traditionally combines with ∫2 chain to form a leukocyte-specific integrin known as inactivated-C3b (iC3b) receptor 4 (CR4). Integrin åX/∫2 shares similar properties of the åM/∫2 integrin in mediating adherence of neutrophils and monocytes to stimulated endothelial cells, and in phagocytosis of complement coated particles. Abnormal expression of Integrin åX is characteristic of hairy cell leukemia (HCL) and is dependent upon activation of proto-oncogenes Ras and JunD. Proteins and DNA elements that influence transcription of Integrin åX include Sp1 and Sp1-like factors, AP-1 family, C/EBP, Oct-2 and PU.1. Integrin åX is present on monocyte derivative dendritic cells (DCs), macrophages and NK cells. Upon activation, DCs present in skin (Langerhans cells), lining of nose, lung, stomach, intestine and blood can migrate to lymphoid tissues and interact with T and B cells to initiate and shape the immune response.

Integrin αX Antibody (3.9) Product Citations
See how others have used Integrin αX Antibody (3.9) and or Integrin αX Antibody (3.9) conjugates.


1 total citations
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Integrin αX Antibody (3.9) Data
Click on image to enlarge
sc-1185
Integrin αX (3.9) FITC: sc-1185 FITC. FCM analysis of THP-1 cells. Black line histogram represents the isotype control, normal mouse IgG1: sc-2855.
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