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home » Lymphocyte Signaling » CD14 Antibody / CD14 Antibodies » CD14 (UCH-M1): sc-1182

CD14 (UCH-M1) Antibody: sc-1182

  |  Datasheet
  • mouse monoclonal IgG2a; 200 µg/ml
  • raised against human thymocytes/Sezary T cells
  • recommended for detection of CD14 (55 kDa) monocyte specific cell surface protein of human origin by WB, IP, IF, IHC(P) and FCM
  • agarose conjugate for IP studies, sc-1182 AC, 500 µg/0.25ml agarose
  • fluorescein (sc-1182 FITC) and phycoerythrin (sc-1182 PE) conjugates for FCM, 100 tests
  • HRP conjugate, sc-1182 HRP, 200 µg/ml
  • Alexa Fluor® 405 (sc-1182 AF405), Alexa Fluor® 488 (sc-1182 AF488) and Alexa Fluor® 647 (sc-1182 AF647) conjugates for FCM or immunofluorescence; 100 µg/2 ml
 
Additional CD14 Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   FCM   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human CD14 929 5q31.3 NM_000591, NM_001040021 P08571
 158120
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
CD14 (UCH-M1) sc-1182 200 µg/ml $279
CD14 (UCH-M1) AC sc-1182 AC 500µg/ml, 25%ag $366
CD14 (UCH-M1) AF405 sc-1182 AF405 100 µg/2 ml $314
CD14 (UCH-M1) AF488 sc-1182 AF488 100 µg/2 ml $314
CD14 (UCH-M1) AF647 sc-1182 AF647 100 µg/2 ml $314
CD14 (UCH-M1) FITC sc-1182 FITC 100 tests in 2 ml $292
CD14 (UCH-M1) HRP sc-1182 HRP 200 µg/ml $279
CD14 (UCH-M1) PE sc-1182 PE 100 tests in 2ml $303
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CD14 siRNA (h) sc-29248 10 µM $258
CD14 (h)-PR sc-29248-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CD14 shRNA Plasmid (h) sc-29248-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CD14 shRNA (h) Lentiviral Particles sc-29248-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CCRF-CEM Cell Lysate sc-2225 500 µg/200 µl $104
BJAB Whole Cell Lysate sc-2207 500 µg/200 µl $104
THP-1 Cell Lysate sc-2238 500 µg/200 µl $104

CD14 Background Information
Lipopolysaccharide (LPS) elicits the secretion of mediators and cytokines produced by activated macrophages and monocytes. CD14 is a glycosylphosphatidylinositol (GPI)-anchored protein found on the surfaces of monocytes and polymorphonuclear leukocytes. CD14 functions as a receptor for LPS, resulting in the secretion of various proteins. An important component in the LPS activation of monocytes through the CD14 receptor is the “adapter molecule,” lipopolysaccharide binding protein (LBP). There are two forms of CD14, a membrane-associated form (mCD14), and a soluble form (sCD14). mCD14 responds to LPS alone and facilitates the secretion of proteins, while cells not expressing mCD14 fail to respond to LPS. The cells that lack mCD14 respond to LPS/LBP in the presence of sCD14 (7).

CD14 (UCH-M1) Product Citations
See how others have used CD14 (UCH-M1): sc-1182 antibody and or CD14 (UCH-M1) antibody conjugates.


18 total citations
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Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
 
CD14 (UCH-M1)
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sc-1182
CD14 (UCH-M1): sc-1182. Western blot analysis of CD14 expression in BJAB whole cell lysate.
sc-1182
CD14 (UCH-M1): sc-1182. Immunoperoxidase staining of formalin-fixed, paraffin-embedded normal human lymph node showing membrane staining of selected cells.
sc-1182
CD14 (UCH-M1) FITC: sc-1182 FITC. FCM analysis of human peripheral blood leukocytes. Black line histogram represents the isotype control, normal mouse IgG2a: sc-2856.
sc-1182
CD14 (UCH-M1) Alexa Fluor 488: sc-1182 AF488. FCM analysis of human peripheral blood leukocytes. Black line histogram represents the isotype control, normal mouse IgG1: sc-3891.
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