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PSR (N-20) Antibody: sc-11632

 |  Datasheet
  • goat polyclonal IgG, 200 µg/ml
  • epitope mapping at the N-terminus of PSR of human origin
  • recommended for detection of PSR of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine, bovine, porcine and avian
  • blocking peptide, sc-11632 P
 
Additional PSR Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human JMJD6 23210 17q25.2 NM_015167 Q6NYC1
604914
Mouse Jmjd6 107817 11 E2 Q9ERI5
N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
PSR (N-20) sc-11632 200 µg/ml $279
PSR (N-20) P sc-11632 P
(peptide)
100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PSR siRNA (h) sc-36324 10 µM $258
PSR siRNA (m) sc-36325 10 µM $258
PSR (h)-PR sc-36324-PR 10 µM $23
PSR (m)-PR sc-36325-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PSR shRNA Plasmid (h) sc-36324-SH 20 µg $520
PSR shRNA Plasmid (m) sc-36325-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PSR shRNA (h) Lentiviral Particles sc-36324-V 200 µl $625
PSR shRNA (m) Lentiviral Particles sc-36325-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
Caki-1 Cell Lysate sc-2224 500 µg/200 µl $104
NIH/3T3 Whole Cell Lysate sc-2210 500 µg/200 µl $104
THP-1 Cell Lysate sc-2238 500 µg/200 µl $104
A549 Cell Lysate sc-2413 500 µg/200 µl $104
PSR (h): 293T Lysate sc-117004 100µg/200µl $205
PSR (m): 293T Lysate sc-125868 100µg/200µl $205

PSR Background Information
Cells undergoing apoptosis lose the asymmetry of plasma membrane phospholipids, and phosphatidylserine is exposed on the outer surface of the membrane. The phosphatidylserine receptor (PSR) specifically recognizes phosphatidylserine and this binding triggers the phagocytosis of apoptotic cells by either macrophages or dendritic cells. PSR is expressed on the surface of macrophages, fibroblasts, and epithelial cells, and it has been detected in high levels in heart, skeletal muscle, and kidney tissues and is extensively glycosylated. The mammalian phosphatidylserine receptor displays significant homology to Caenorhabditis elegans and Drosophila melanogaster proteins, which suggests that PSR has been conserved throughout phylogeny.

PSR (N-20)
Click on image to enlarge
PSR (N-20): sc-11632. Western blot analysis of PSR expression in Caki-1 (A) and HT-1080 (B) whole cell lysates.
PSR (N-20): sc-11632. Western blot analysis of PSR expression in Caki-1 (A), THP-1 (B), HT-1080 (C), HeLa (D), A549 (E) and NIH/3T3 (F) whole cell lysates.
PSR (N-20): sc-11632. Western blot analysis of PSR expression in non-transfected 293T: sc-117752 (A), human PSR transfected 293T: sc-117004 (B) and NIH/3T3 (C) whole cell lysates.
PSR (N-20): sc-11632. Western blot analysis of PSR expression in non-transfected: sc-117752 (A) and mouse PSR transfected: sc-125868 (B) 293T whole cell lysates.
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