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- goat polyclonal IgG, 200 µg/ml
- epitope mapping at the N-terminus of PSR of human origin
- recommended for detection of PSR of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine, bovine, porcine and avian
- blocking peptide, sc-11632 P
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Ordering Information
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
JMJD6 |
23210 |
17q25.2 |
NM_015167 |
Q6NYC1
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604914 |
| Mouse |
Jmjd6 |
107817 |
11 E2 |
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Q9ERI5
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N/A |
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PSR Background Information Cells undergoing apoptosis lose the asymmetry of plasma membrane phospholipids, and phosphatidylserine is exposed on the outer surface of the membrane. The phosphatidylserine receptor (PSR) specifically recognizes phosphatidylserine and this binding triggers the phagocytosis of apoptotic cells by either macrophages or dendritic cells. PSR is expressed on the surface of macrophages, fibroblasts, and epithelial cells, and it has been detected in high levels in heart, skeletal muscle, and kidney tissues and is extensively glycosylated. The mammalian phosphatidylserine receptor displays significant homology to Caenorhabditis elegans and Drosophila melanogaster proteins, which suggests that PSR has been conserved throughout phylogeny. |
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PSR (N-20)
Click on image to enlarge
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PSR (N-20): sc-11632. Western blot analysis of PSR expression in Caki-1 (A) and HT-1080 (B) whole cell lysates.
PSR (N-20): sc-11632. Western blot analysis of PSR expression in Caki-1 (A), THP-1 (B), HT-1080 (C), HeLa (D), A549 (E) and NIH/3T3 (F) whole cell lysates.
PSR (N-20): sc-11632. Western blot analysis of PSR expression in non-transfected 293T: sc-117752 (A), human PSR transfected 293T: sc-117004 (B) and NIH/3T3 (C) whole cell lysates.
PSR (N-20): sc-11632. Western blot analysis of PSR expression in non-transfected: sc-117752 (A) and mouse PSR transfected: sc-125868 (B) 293T whole cell lysates.
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