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- goat polyclonal IgG, 200 µg/ml
- epitope mapping at the C-terminus of NFATc4 of human origin
- recommended for detection of NFATc4 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine and porcine
- blocking peptide, sc-1153 P
- TransCruz reagent for Gel Supershift and ChIP applications, sc-1153 X, 200 µg/0.1 ml
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NFATc4 Background Information NFATc4 (nuclear factor of activated T cells, cytoplasmic, calcineurin-dependent 4) is a member of the nuclear factors of activated T cells DNA-binding transcription complex that influences cytokine gene expression, cardiac hypertrophy and adipocyte differentiation. This complex consists of at least two components: a cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate in the formation of this complex. NFATc4 plays a role in the inducible expression of cytokine genes in T cells, including the induction of IL-2 and IL-4. p38 MAP kinase phosphorylates multiple residues in the NFAT homology domain of NFATc4.
| NFATc4 (C-20) Product Citations |
See how others have used NFATc4 (C-20): sc-1153 antibody and or NFATc4 (C-20) antibody conjugates.
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NFATc4 (C-20)
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NFATc4 (C-20): sc-1153. Western blot analysis of NFATc4 expression in non-transfected: sc-117752 (A) and human NFATc4 transfected: sc-116481 (B) 293T whole cell lysates.
NFATc4 (C-20): sc-1153. Western blot analysis of NFATc4 expression in non-transfected: sc-117752 (A) and mouse NFATc4 transfected: sc-122039 (B) 293T whole cell lysates.
Western blot analysis of NFATc4 phosphorylation in untreated (A,C), and lambda protein phosphatase treated (B,D) Jurkat whole cell lysates. Antibodies tested include p-NFATc4 (Ser 168/170): sc-32630 (A,B) and NFATc4 (C-20): sc-1153 (C,D).
Western blot analysis of NFATc4 phosphorylation in untreated (A,C), and lambda protein phosphatase treated (B,D) Jurkat nuclear extract. Antibodies tested include p-NFATc4 (Ser 168/170): sc-32630 (A,B) and NFATc4 (C-20): sc-1153 (C,D).
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