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- rabbit polyclonal IgG, 200 µg/ml
- epitope corresponding to amino acids 1-300 mapping at the N-terminus of eIF4G of human origin
- recommended for detection of eIF4G of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
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eIF4G Background Information
The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. The eukaryotic initiation complex eIF4F exists in vitro as a trimeric complex of eIF4G, eIF4E, and eIF4A. Together, the complex allows ribosome binding to mRNA by inducing the unwinding of mRNA secondary structures (1,2). eIF4E binds to the mRNA “cap” during an early step in the initiation of protein synthesis (3,4). eIF4A acts as an ATP-dependent RNA helicase (5,6). eIF4G acts as a bridge between eIF4E, eIF4A, and the eIF3 complex (7,8).
| eIF4G (H-300) Product Citations |
See how others have used eIF4G (H-300): sc-11373 antibody and or eIF4G (H-300) antibody conjugates.
13 total citations Loading citations.
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eIF4G (H-300)
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eIF4G (H-300): sc-11373. Immunofluorescence staining of normal mouse liver frozen section showing nuclear staining.
eIF4G (H-300): sc-11373. Western blot analysis of eIF4G expression in non-transfected 293T: sc-117752 (A), mouse eIF4G transfected 293T: sc-119991 (B), Jurkat (C) and NIH/3T3 (D) whole cell lysates. |
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