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home » Transcription Regulators » T-bet Antibody / T-bet Antibodies » T-bet (N-19): sc-11330

T-bet (N-19) Antibody: sc-11330

  |  Datasheet
  • goat polyclonal IgG, 200 µg/ml
  • epitope mapping near the N-terminus of T-bet of human origin
  • recommended for detection of T-bet of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine, bovine and porcine
  • blocking peptide, sc-11330 P
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-11330 X, 200 µg/0.1 ml
 
Additional T-bet Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   Gel Shift   ChIP   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human TBX21 30009 17q21.32 NM_013351 Q9UL17
 604895
Mouse Tbx21 57765 11 D Q9JKD8
 N/A
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
T-bet (N-19) sc-11330 200 µg/ml $279
T-bet (N-19) P sc-11330 P
(peptide)
 100 µg/0.5 ml $61
T-bet (N-19) X sc-11330 X 200 µg/0.1 ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
T-bet siRNA (h) sc-36598 10 µM $258
T-bet siRNA (m) sc-36599 10 µM $258
T-bet (h)-PR sc-36598-PR 10 µM $23
T-bet (m)-PR sc-36599-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
T-bet shRNA Plasmid (h) sc-36598-SH 20 µg $520
T-bet shRNA Plasmid (m) sc-36599-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
T-bet shRNA (h) Lentiviral Particles sc-36598-V 200 µl $625
T-bet shRNA (m) Lentiviral Particles sc-36599-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
BJAB nuclear extract sc-2145 1000 µg $143
Jurkat nuclear extract sc-2132 1000 µg $143
T-bet (h): 293T Lysate sc-115503 100µg/200µl $205
BJAB Whole Cell Lysate sc-2207 500 µg/200 µl $104

T-bet Background Information
T helper (Th) lymphocytes differentiate into two unique subsets, Th1 and Th2, which differ both in function and in the cytokines they secrete. Th1 and Th2 cytokines promote the growth and differentiation of their subset, and inhibit the growth and differentiation of the opposing subset. T-bet (T box expressed in T cells) is a Th1-specific T box transcription factor that controls the expres-sion of the Th1 cytokine, IFN-©. T-bet also converts effector Th2 cells into the opposing Th1 subset. T-bet is selectively expressed in Th1 cells. The level of T-bet expression is increased by signals mediated by the T cell receptor (TCR). IL-12 also induces an increase in the level of T-bet. T-bet was originally isolated from nuclear extracts of resting and PMA/ionomycin-activated AE7 cells. T-bet is expressed in low levels in AE7 cells, and in increased levels in stimulated AE7.

T-bet (N-19) Product Citations
See how others have used T-bet (N-19): sc-11330 antibody and or T-bet (N-19) antibody conjugates.


4 total citations
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T-bet (N-19)
Click on image to enlarge
sc-11330
Western blot analysis of T-bet expression in BJAB nuclear extract immunoprecipitated with T-bet (4B10): sc-21749 and detected with T-bet (N-19): sc-11330.
sc-11330
T-bet (N-19): sc-11330. Western blot analysis of T-bet expression in non-transfected: sc-117752 (A) and human T-bet transfected: sc-115503 (B) 293T whole cell lysates.
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