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home » Cell Cycle Proteins » CENP Antibody / CENP Antibodies » CENP-C (L-19): sc-11285

CENP-C (L-19) Antibody: sc-11285

  |  Datasheet
  • goat polyclonal IgG, 200 µg/ml
  • epitope mapping within an internal region of CENP-C of human origin
  • recommended for detection of CENP-C of mouse, rat and human origin by WB, IF and ELISA
  • blocking peptide, sc-11285 P
 
Additional CENP Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human CENPC1 1060 4q13.2 NM_001812 Q03188
 117141
Mouse Cenpc1 12617 5 E1 P49452
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
CENP-C (L-19) sc-11285 200 µg/ml $279
CENP-C (L-19) P sc-11285 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CENP-C siRNA (h) sc-37559 10 µM $258
CENP-C siRNA (m) sc-37560 10 µM $258
CENP-C (h)-PR sc-37559-PR 10 µM $23
CENP-C (m)-PR sc-37560-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CENP-C shRNA Plasmid (h) sc-37559-SH 20 µg $520
CENP-C shRNA Plasmid (m) sc-37560-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CENP-C shRNA (h) Lentiviral Particles sc-37559-V 200 µl $625
CENP-C shRNA (m) Lentiviral Particles sc-37560-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
HEL 92.1.7 Cell Lysate sc-2270 500 µg/200 µl $104
SK-N-SH Cell Lysate sc-2410 500 µg/200 µl $104
K-562 Whole Cell Lysate sc-2203 500 µg/200 µl $104

CENP-C Background Information
A replicated chromosome includes two kinetochores that control chromosome segregation during mitosis. The evolutionarily conserved Centromere Protein-C, CENP-C, is a kinetochore assembly protein. CENP-C is located on the fibers of the kinetochore and constitutes a kinetochore organizing center that tightly associates with DNA. CENP-C is necessary for the formation of a functional centromere, which indicates that CENP-C is important for mitotic progression. In addition, CENP-C is lost from centromeres during herpes simplex virus 1 infection, causing substantial structural changes in the kinetochore, which suggests that the structure of CENP-C is regulated during the cell cycle.
CENP-C (L-19)
Click on image to enlarge
sc-11285
CENP-C (L-19): sc-11285. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization.
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