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- goat polyclonal IgG, 200 µg/ml
- epitope mapping near the N-terminus of ABCG1 of human origin
- recommended for detection of ABCG1 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine and bovine
- blocking peptide, sc-11150 P
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ABCG1 Background Information
ABCG1 (also designated ABC8 or human white gene), a member of the evolutionary conserved family of ATP-binding cassette (ABC) transporters, exhibits high homology with the Drosophila white gene (1–3). ABC transporters couple the energy of ATP hydrolysis to the translocation of various molecules across biological membranes (4–6). These proteins contain characteristic ATP-binding domains and transmembrane domains which form a channel-like structure for transport (4). ABCG1 functions to regulate cholesterol and phospholipid transport in macrophages (7). ABCG1 is highly expressed in several tissues, including brain, spleen, lung and placenta, and has been localized to the cell surface and intracellular compartments of cholesterol-laden macrophages (3,7).
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See how others have used ABCG1 (E-20): sc-11150 antibody and or ABCG1 (E-20) antibody conjugates.
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ABCG1 (E-20)
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ABCG1 (E-20): sc-11150. Western blot analysis of ABCG1 expression in c4 whole cell lysate.
ABCG1 (E-20): sc-11150. Immunofluorescence staining of methanol-fixed c4 cells showing membrane and cytoplasmic localization.
ABCG1 (E-20): sc-11150. Western blot analysis of ABCG1 expression in HeLa whole cell lysate.
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