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- goat polyclonal IgG, 200 µg/ml
- epitope mapping near the N-terminus of FBP1 of human origin
- recommended for detection of FBP1 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
- blocking peptide, sc-11098 P
- TransCruz reagent for Gel Supershift and ChIP applications, sc-11098 X, 200 µg/0.1ml
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Ordering Information
Recommended Support Products:
(click button of application of choice)
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
FUBP1 |
8880 |
1p31.1 |
NM_003902 |
Q96AE4
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603444 |
| Mouse |
Fubp1 |
51886 |
3 H3 |
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Q91WJ8
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N/A |
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FBP1 Background Information
Activation of FUSE, the far upstream element, is required for the proper ex-pression of the mammalian gene c-Myc in undifferentiated cells. The binding of FBP1 (FUSE-binding protein or far upstream element-binding protein) to FUSE is necessary for c-Myc expression, indicating that FBP1 functions as a growth-dependent regulator of c-Myc expression. Isolated from proliferating HL-60 cells, FBP1 (FBP), FBP2 and FBP3 comprise a family of single-stranded DNA-binding proteins that specifically bind to FUSE elements. The FBP transcription factors share a conserved central DNA-binding domain and show significant homology in their carboxyl-terminal activation domains. Expression of FBP1 is detected in undifferentiated cells and is substantially decreased following cellular differentiation. |
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FBP1 (N-15)
Click on image to enlarge
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FBP1 (N-15): sc-11098. Western blot analysis of FBP1 expression in non-transfected 293T: sc-117752 (A), mouse FBP1 transfected 293T: sc-120212 (B) and HL-60 (C) whole cell lysates. FBP1 (N-15): sc-11098. Western blot analysis of FBP1 expression in non-transfected 293T: sc-117752 (A), mouse FBP1 transfected 293T: sc-120211 (B) and HL-60 (C) whole cell lysates. |
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