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p-53BP1 Antibody (Ser 1778): sc-109897

 |  Datasheet

(Based on data analysis)
  • p-53BP1 Antibody (Ser 1778) is a rabbit polyclonal IgG provided at 100 µg/ml
  • epitope corresponding to phosphorylated Ser 1778 of 53BP1 of human origin
  • recommended for detection of Ser 1778 phosphorylated 53BP1 of human origin by WB, IF and ELISA; also reactive with additional species, including equine and canine
  • blocking peptide, sc-109897 P
 

See additional 53bp Antibodies including 53bp, 53BP1 and 53BP2.

Ordering InformationGene Info
Recommended Support Products:
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WB   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
p-53BP1 Antibody (Ser 1778) sc-109897 100 µg/ml $279
p-53BP1 (Ser 1778) P sc-109897 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
53BP1 siRNA (h) sc-37455 10 µM $258
53BP1 (h)-PR sc-37455-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
53BP1 shRNA Plasmid (h) sc-37455-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
53BP1 shRNA (h) Lentiviral Particles sc-37455-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human TP53BP1 7158 15q15.3 Q12888
 605230
 

53BP1, also known as TP53BP1 (tumor protein p53 binding protein 1) or p202, is a 1,972 amino acid protein that is associated with kinetochores and contains two BRCT domains. Existing as multiple alternatively spliced isoforms, 53BP1 interacts with p53 and is thought to play a role in checkpoint signaling during mitosis, possibly enhancing p53-mediated transcriptional activation and influencing the cellular response to DNA damage. 53BP1 is subject to post-translational phosphorylation on specific amino acid residues, including Ser 1778, Ser 25 and Ser 29. The gene encoding 53BP1 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome.