epitope mapping near the C-terminus of v-SNARE Ykt6p of human origin
recommended for detection of SNARE Ykt6p of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
v-SNARE Ykt6p Background Information Membrane traffic in eukaryotic cells requires the interaction of a vesicle-associated soluble N-ethylmaleimide-sensitive fusion (NSF) attachment protein receptor (v-SNARE) on transport vesicles with a SNARE on the target membrane (t-SNARE) (1). Both v- and t-SNAREs are compartment-specific and bind each other directly and specifically (2). The v-SNAREs Ykt6p and Vti1p are involved in ER-Golgi and intra-Golgi membrane trafficking (1,3). For v-SNARE Ykt6p, membrane interaction is mediated through a cysteine/aliphatic/aliphatic/methionine or histidine (CAAX) C-terminal motif, a consensus sequence involved in prenylated membrane anchoring (4). The v-SNARE Vti1p interacts with the prevacuolar t-SNARE Pep12p in Golgi prevacuolar transport and with the cis-Golgi t-SNARE Sed5p in traffic to the cis-Golgi (5).
v-SNARE Ykt6p (K-16) Product Citations
See how others have used v-SNARE Ykt6p (K-16): sc-10835 antibody and or v-SNARE Ykt6p (K-16) antibody conjugates.
