This polyclonal antibody has been discontinued. See our recommended GTBP (E-8) monoclonal antibody (sample data shown).
GTBP Antibody (H-141): sc-10798
- GTBP Antibody (H-141) is a rabbit polyclonal IgG; 200 µg/ml
- epitope corresponding to amino acids 1220-1360 mapping at the C-terminus of GTBP (G/T binding protein) of human origin
- Discontinued polyclonal antibody
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Description
The finding that mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC) has resulted in considerable interest in the understanding of the mechanism of DNA mismatch repair. Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes mutS and mutL were demonstrated at high frequency in HNPCC and were shown to be associated with microsatellite instability. A member of the mismatch repair family, GTBP (also designated MSH6), is a MSH2-related protein that binds to DNA containing G/T mismatches. Findings suggest that the mismatch-binding factor in human cells is composed of a heterodimer of GTBP and MSH2.
Ordering Information
GTBP (E-8): sc-137015 [ Recommended monoclonal replacement for GTBP (H-141) ]
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GTBP Antibody (E-8) | sc-137015 | 200 µg/ml | $322.00 | |||
GTBP Antibody (E-8): m-IgG Fc BP-HRP Bundle | sc-528837 | 200 µg Ab; 10 µg BP | $361.00 | |||
GTBP Antibody (E-8): m-IgGκ BP-HRP Bundle | sc-521395 | 200 µg Ab, 40 µg BP | $361.00 | |||
GTBP Antibody (E-8): m-IgG2a BP-HRP Bundle | sc-547181 | 200 µg Ab; 10 µg BP | $361.00 | |||
GTBP Antibody (E-8) AC | sc-137015 AC | 500 µg/ml, 25% agarose | $424.00 | |||
GTBP Antibody (E-8) HRP | sc-137015 HRP | 200 µg/ml | $322.00 | |||
GTBP Antibody (E-8) FITC | sc-137015 FITC | 200 µg/ml | $336.00 | |||
GTBP Antibody (E-8) PE | sc-137015 PE | 200 µg/ml | $349.00 | |||
GTBP Antibody (E-8) Alexa Fluor® 488 | sc-137015 AF488 | 200 µg/ml | $364.00 | |||
GTBP Antibody (E-8) Alexa Fluor® 546 | sc-137015 AF546 | 200 µg/ml | $364.00 | |||
GTBP Antibody (E-8) Alexa Fluor® 594 | sc-137015 AF594 | 200 µg/ml | $364.00 | |||
GTBP Antibody (E-8) Alexa Fluor® 647 | sc-137015 AF647 | 200 µg/ml | $364.00 | |||
GTBP Antibody (E-8) Alexa Fluor® 680 | sc-137015 AF680 | 200 µg/ml | $364.00 | |||
GTBP Antibody (E-8) Alexa Fluor® 790 | sc-137015 AF790 | 200 µg/ml | $364.00 |