Date published: 2026-7-20

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TRAF Antibodies

Santa Cruz Biotechnology features a diverse variety of TRAF monoclonal antibodies for research focused on TNF receptor-associated factors (TRAFs) in various cellular processes. TRAF monoclonal antibodies are suitable for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). TRAF proteins function as critical mediators in signal transduction pathways, particularly those involved in immune responses and inflammation. TRAF proteins play a significant role in the regulation of apoptosis, cell survival, and the activation of NF-kB signaling pathways, maintaining cellular homeostasis and responding to stress signals. Understanding TRAF protein function is vital for elucidating their contributions to various diseases, including cancer and autoimmune disorders. TRAF monoclonal antibodies enable precise detection and analysis of specific TRAF family members across multiple experimental applications. Researchers can effectively investigate TRAF-mediated signaling pathways and their biological implications using advanced immunological techniques. Santa Cruz Biotechnology monoclonal antibodies for TRAF proteins support cutting-edge research that advances our understanding of cellular signaling mechanisms and disease development.

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TRAF Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

TRAF1 Antibody (H-3)

sc-6253mouse IgG1 κ173-295 (h)WB, IP, IF, IHC(P), FCMm, r, h
31
(11)

TRAF1 Antibody (B-12)

sc-515161mouse IgG2a κ53-185 (h)WB, IP, IF, ELISAm, r, h

new

(0)

TRAF1 Antibody (E-10)

sc-514936mouse IgG1 κ6-30 (h)WB, IP, IF, ELISAm, r, h

new

(0)

TRAF1 Antibody (E-12)

sc-271683mouse IgG1 κ2-31 (m)WB, IP, IF, ELISAm, r, h
2
(3)

TRAF2 Antibody (F-2)

sc-136999mouse IgG1 κ1-249 (h)WB, IP, IF, IHC(P), ELISAm, r, h
20
(15)

TRAF2 Antibody (H-10)

sc-7346mouse IgG1 λ478-497 (m)WB, IP, IF, IHC(P), FCM, ELISAm, r, h
36
(15)

TRAF2 Antibody (D-3)

sc-136997mouse IgG1 κ1-249 (h)WB, IP, IF, IHC(P), ELISAh
1
(3)

TRAF2 Antibody (D-12)

sc-365287mouse IgG3 κ2-27 (h)WB, IP, IF, ELISAm, r, h
2
(2)

TRAF2 Antibody (F-4)

sc-137048mouse IgG1 κ1-249 (h)WB, IP, IF, IHC(P), ELISAm, r, h
2
(5)

TRAF2 Antibody (G-3)

sc-136998mouse IgG2b κ1-249 (h)WB, IP, IF, ELISAm, r, h

new

(5)

TRAF3 Antibody (G-6)

sc-6933mouse IgG2b κ322-444 (h)WB, IP, IF, FCMm, r, h
41
(18)

TRAF4 Antibody (B-9)

sc-390232mouse IgG1 κ40-111 (h)WB, IP, IF, ELISAm, r, h
5
(4)

TRAF4 Antibody (43)

sc-136107mouse IgG12-160 (h)WB, IP, IFm, r, h and canine
2
(1)

TRAF4 Antibody (D-2)

sc-390212mouse IgG1 κN-Terminal (h)WB, IP, IF, ELISAm, r, h

new

(1)

TRAF5 Antibody (E-4)

sc-74502mouse IgG1 κ1-257 (h)WB, IP, IF, ELISAm, r, h
5
(5)

TRAF5 Antibody (E-5)

sc-74503mouse IgG1 κ1-257 (h)WB, IP, IF, ELISAm, r, h
2
(3)

TRAF5 Antibody (B-6)

sc-271145mouse IgG1 κ526-558 (m)WB, IP, IF, ELISAm, r, h

new

(1)

TRAF5 Antibody (C-4)

sc-133252mouse IgG2a κ1-257 (h)WB, IP, IF, IHC(P), ELISAm, r, h

new

(2)

TRAF5 Antibody (E-8)

sc-271144mouse IgG3 κ526-558 (m)WB, IP, IF, ELISAm, r, h

new

(1)

TRAF6 Antibody (D-10)

sc-8409mouse IgG1 κ1-274 (h)WB, IP, IF, IHC(P), ELISAm, r, h
245
(30)

TRAF siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

TRAF1 siRNA (h)

sc-29508hGene SilencingN/A
3
(0)

TRAF1 shRNA Plasmid (h)

sc-29508-SHhGene SilencingPuromycin
3
(0)

TRAF1 shRNA (h) Lentiviral Particles

sc-29508-VhGene SilencingPuromycin
3
(0)

TRAF1 siRNA (m)

sc-36710mGene SilencingN/A0
(0)

TRAF1 shRNA Plasmid (m)

sc-36710-SHmGene SilencingPuromycin0
(0)

TRAF1 shRNA (m) Lentiviral Particles

sc-36710-VmGene SilencingPuromycin0
(0)

TRAF2 siRNA (h)

sc-29509hGene SilencingN/A
20
(1)

TRAF2 siRNA (h2)

sc-44276hGene SilencingN/A0
(0)

TRAF2 shRNA Plasmid (h)

sc-29509-SHhGene SilencingPuromycin
20
(1)

TRAF2 shRNA Plasmid (h2)

sc-44276-SHhGene SilencingPuromycin0
(0)

TRAF2 shRNA (h) Lentiviral Particles

sc-29509-VhGene SilencingPuromycin
20
(1)

TRAF2 shRNA (h2) Lentiviral Particles

sc-44276-VhGene SilencingPuromycin0
(0)

TRAF2 siRNA (m)

sc-36711mGene SilencingN/A
4
(0)

TRAF2 shRNA Plasmid (m)

sc-36711-SHmGene SilencingPuromycin
4
(0)

TRAF2 shRNA (m) Lentiviral Particles

sc-36711-VmGene SilencingPuromycin
4
(0)

TRAF3 siRNA (h)

sc-29510hGene SilencingN/A
7
(1)

TRAF3 siRNA (h2)

sc-44277hGene SilencingN/A0
(1)

TRAF3 shRNA Plasmid (h)

sc-29510-SHhGene SilencingPuromycin
7
(1)

TRAF3 shRNA Plasmid (h2)

sc-44277-SHhGene SilencingPuromycin0
(1)

TRAF3 shRNA (h) Lentiviral Particles

sc-29510-VhGene SilencingPuromycin
7
(1)

TRAF3 shRNA (h2) Lentiviral Particles

sc-44277-VhGene SilencingPuromycin0
(1)

TRAF3 siRNA (m)

sc-36712mGene SilencingN/A
9
(0)

TRAF3 shRNA Plasmid (m)

sc-36712-SHmGene SilencingPuromycin
9
(0)

TRAF3 shRNA (m) Lentiviral Particles

sc-36712-VmGene SilencingPuromycin
9
(0)

TRAF4 siRNA (h)

sc-36713hGene SilencingN/A
5
(0)

TRAF4 shRNA Plasmid (h)

sc-36713-SHhGene SilencingPuromycin
5
(0)

TRAF4 shRNA (h) Lentiviral Particles

sc-36713-VhGene SilencingPuromycin
5
(0)

TRAF4 siRNA (m)

sc-36714mGene SilencingN/A0
(0)

TRAF4 shRNA Plasmid (m)

sc-36714-SHmGene SilencingPuromycin0
(0)

TRAF4 shRNA (m) Lentiviral Particles

sc-36714-VmGene SilencingPuromycin0
(0)

TRAF5 siRNA (h)

sc-36715hGene SilencingN/A
2
(0)

TRAF5 shRNA Plasmid (h)

sc-36715-SHhGene SilencingPuromycin
2
(0)

TRAF5 shRNA (h) Lentiviral Particles

sc-36715-VhGene SilencingPuromycin
2
(0)

TRAF5 siRNA (m)

sc-36716mGene SilencingN/A
1
(0)

TRAF5 shRNA Plasmid (m)

sc-36716-SHmGene SilencingPuromycin
1
(0)

TRAF5 shRNA (m) Lentiviral Particles

sc-36716-VmGene SilencingPuromycin
1
(0)

TRAF6 siRNA (h)

sc-36717hGene SilencingN/A
32
(1)

TRAF6 siRNA (h2)

sc-44329hGene SilencingN/A0
(0)

TRAF6 shRNA Plasmid (h)

sc-36717-SHhGene SilencingPuromycin
32
(1)

TRAF6 shRNA Plasmid (h2)

sc-44329-SHhGene SilencingPuromycin0
(0)

TRAF6 shRNA (h) Lentiviral Particles

sc-36717-VhGene SilencingPuromycin
32
(1)

TRAF6 shRNA (h2) Lentiviral Particles

sc-44329-VhGene SilencingPuromycin0
(0)

TRAF6 siRNA (m)

sc-36718mGene SilencingN/A
12
(0)

TRAF6 shRNA Plasmid (m)

sc-36718-SHmGene SilencingPuromycin
12
(0)

TRAF6 shRNA (m) Lentiviral Particles

sc-36718-VmGene SilencingPuromycin
12
(0)

TRAF6 siRNA (r)

sc-156004rGene SilencingN/A
7
(0)

TRAF6 shRNA Plasmid (r)

sc-156004-SHrGene SilencingPuromycin
7
(0)

TRAF6 shRNA (r) Lentiviral Particles

sc-156004-VrGene SilencingPuromycin
7
(0)

TRAF7 siRNA (h)

sc-61704hGene SilencingN/A0
(0)

TRAF7 shRNA Plasmid (h)

sc-61704-SHhGene SilencingPuromycin0
(0)

TRAF7 shRNA (h) Lentiviral Particles

sc-61704-VhGene SilencingPuromycin0
(0)

TRAF7 siRNA (m)

sc-61705mGene SilencingN/A0
(0)

TRAF7 shRNA Plasmid (m)

sc-61705-SHmGene SilencingPuromycin0
(0)

TRAF7 shRNA (m) Lentiviral Particles

sc-61705-VmGene SilencingPuromycin0
(0)

TRAF Transfected Lysates

Empty Table HeaderProduct NameCATALOG #SpeciesCONTROL ANTIBODYCitationsRATING

TRAF2 (h4): 293T Lysate

sc-116412h40
(0)

TRAF CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

TRAF1 CRISPR/Cas9 KO Plasmid (h)

sc-401824Gene Knockouth0
(0)

TRAF1 HDR Plasmid (h)

sc-401824-HDRHomology Directed Repairh0
(0)

TRAF1 CRISPR/Cas9 KO Plasmid (m)

sc-423492Gene Knockoutm0
(0)

TRAF2 CRISPR/Cas9 KO Plasmid (h)

sc-400361Gene Knockouth0
(0)

TRAF2 HDR Plasmid (h)

sc-400361-HDRHomology Directed Repairh0
(0)

TRAF2 CRISPR/Cas9 KO Plasmid (m)

sc-423493Gene Knockoutm0
(0)

TRAF2 HDR Plasmid (m)

sc-423493-HDRHomology Directed Repairm0
(0)

TRAF3 CRISPR/Cas9 KO Plasmid (h2)

sc-400473-KO-2Gene Knockouth0
(0)

TRAF3 HDR Plasmid (h2)

sc-400473-HDR-2Homology Directed Repairh0
(0)

TRAF3 CRISPR/Cas9 KO Plasmid (m)

sc-423494Gene Knockoutm0
(0)

TRAF3 HDR Plasmid (m)

sc-423494-HDRHomology Directed Repairm0
(0)

TRAF4 CRISPR/Cas9 KO Plasmid (h2)

sc-401930-KO-2Gene Knockouth0
(0)

TRAF4 HDR Plasmid (h2)

sc-401930-HDR-2Homology Directed Repairh0
(0)

TRAF4 CRISPR/Cas9 KO Plasmid (m)

sc-423495Gene Knockoutm0
(0)

TRAF5 CRISPR/Cas9 KO Plasmid (h)

sc-402073Gene Knockouth0
(0)

TRAF5 HDR Plasmid (h)

sc-402073-HDRHomology Directed Repairh0
(0)

TRAF5 CRISPR/Cas9 KO Plasmid (m)

sc-423496Gene Knockoutm0
(0)

TRAF5 HDR Plasmid (m)

sc-423496-HDRHomology Directed Repairm0
(0)

TRAF6 CRISPR/Cas9 KO Plasmid (h)

sc-400117Gene Knockouth0
(0)

TRAF6 HDR Plasmid (h)

sc-400117-HDRHomology Directed Repairh0
(0)

TRAF6 CRISPR/Cas9 KO Plasmid (m)

sc-423497Gene Knockoutm0
(0)

TRAF7 CRISPR/Cas9 KO Plasmid (h)

sc-404992Gene Knockouth0
(0)

TRAF7 CRISPR/Cas9 KO Plasmid (m)

sc-432463Gene Knockoutm0
(0)

TRAF7 HDR Plasmid (m)

sc-432463-HDRHomology Directed Repairm0
(0)

TRAF CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

TRAF2 Double Nickase Plasmid (h)

sc-400361-NICGene Knockouth0
(0)

TRAF2 Double Nickase Plasmid (h2)

sc-400361-NIC-2Gene Knockouth0
(0)

TRAF2 Double Nickase Plasmid (m)

sc-423493-NICGene Knockoutm0
(0)

TRAF2 Double Nickase Plasmid (m2)

sc-423493-NIC-2Gene Knockoutm0
(0)

TRAF3 Double Nickase Plasmid (h)

sc-400473-NICGene Knockouth0
(0)

TRAF3 Double Nickase Plasmid (h2)

sc-400473-NIC-2Gene Knockouth0
(0)

TRAF6 Double Nickase Plasmid (h)

sc-400117-NICGene Knockouth0
(0)

TRAF6 Double Nickase Plasmid (h2)

sc-400117-NIC-2Gene Knockouth0
(0)

TRAF6 Double Nickase Plasmid (m)

sc-423497-NICGene Knockoutm0
(0)

TRAF6 Double Nickase Plasmid (m2)

sc-423497-NIC-2Gene Knockoutm0
(0)

TRAF7 Double Nickase Plasmid (h)

sc-404992-NICGene Knockouth0
(0)

TRAF7 Double Nickase Plasmid (h2)

sc-404992-NIC-2Gene Knockouth0
(0)

TRAF CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

TRAF2 CRISPR Activation Plasmid (h)

sc-400361-ACTGene Activationh0
(0)

TRAF3 CRISPR Activation Plasmid (h)

sc-400473-ACTGene Activationh0
(0)

TRAF3 CRISPR Activation Plasmid (h2)

sc-400473-ACT-2Gene Activationh0
(0)

TRAF3 CRISPR Activation Plasmid (m)

sc-423494-ACTGene Activationm0
(0)

TRAF4 CRISPR Activation Plasmid (h)

sc-401930-ACTGene Activationh0
(0)

TRAF6 CRISPR Activation Plasmid (h)

sc-400117-ACTGene Activationh0
(0)

TRAF6 Lentiviral Activation Particles (h)

sc-400117-LACGene Activationh0
(0)

TRAF7 CRISPR Activation Plasmid (h)

sc-404992-ACTGene Activationh0
(0)