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home » Synthesis and Degradation » Cathepsin Antibody / Cathepsin Antibodies » cathepsin D (H-75): sc-10725

cathepsin D (H-75) Antibody: sc-10725

  |  Datasheet
  • rabbit polyclonal IgG, 200 µg/ml
  • epitope corresponding to amino acids 1-75 mapping at the N-terminus of cathepsin D of human origin
  • recommended for detection of cathepsin D of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including porcine
 
Additional Cathepsin Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human CTSD 1509 11p15.5 NM_001909 P07339
 610127
Mouse Ctsd 13033 7 F5 P18242
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
cathepsin D (H-75) sc-10725 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
cathepsin D siRNA (h) sc-29239 10 µM $258
cathepsin D siRNA (m) sc-29934 10 µM $258
cathepsin D (h)-PR sc-29239-PR 10 µM $23
cathepsin D (m)-PR sc-29934-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
cathepsin D shRNA Plasmid (h) sc-29239-SH 20 µg $520
cathepsin D shRNA Plasmid (m) sc-29934-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
cathepsin D shRNA (h) Lentiviral Particles sc-29239-V 200 µl $625
cathepsin D shRNA (m) Lentiviral Particles sc-29934-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
K-562 Whole Cell Lysate sc-2203 500 µg/200 µl $104
MCF7 Whole Cell Lysate sc-2206 500 µg/200 µl $104
ZR-75-1 Cell Lysate sc-2241 500 µg/200 µl $104
rat kidney extract sc-2394 500 µg/200 µl $104
NIH/3T3 Whole Cell Lysate sc-2210 500 µg/200 µl $104
cathepsin D (h2): 293T Lysate sc-170717 100µg/200µl $205
RAW 264.7 Whole Cell Lysate sc-2211 500 µg/200 µl $104

cathepsin D Background Information
The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. Cathepsins may also cleave some protein precursors, thereby releasing regulatory peptides. The promoter region of the cathepsin D gene contains five Sp1 binding sites and four AP-2 binding sites.

cathepsin D (H-75) Product Citations
See how others have used cathepsin D (H-75): sc-10725 antibody and or cathepsin D (H-75) antibody conjugates.


18 total citations
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cathepsin D (H-75)
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sc-10725
cathepsin D (H-75): sc-10725. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human breast tumor showing cytoplasmic staining.
sc-10725
cathepsin D (H-75): sc-10725. Western blot analysis of cathepsin D precursor expression in ZR-75-1 (A) and MCF7 (B) whole cell lysates.
sc-10725
cathepsin D (H-75): sc-10725. Immunofluorescence staining of normal mouse intestine frozen section showing cytoplasmic staining.
sc-10725
cathepsin D (H-75): sc-10725. Western blot analysis of cathepsin D expression in non-transfected 293T: sc-117752 (A), mouse cathepsin D transfected 293T: sc-126582 (B) and MCF7 (C) whole cell lysates.
sc-10725
cathepsin D (H-75): sc-10725. Western blot analysis of cathepsin D expression in non-transfected 293T: sc-117752 (A), human cathepsin D transfected 293T: sc-170717 (B) and K-562 (C) whole cell lysates.
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