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DOCK 8 Antibody (T-13): sc-104911

 |  Datasheet

(Based on data analysis)

  • DOCK 8 Antibody (T-13) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping near the N-terminus of DOCK 8 of human origin
  • recommended for detection of DOCK 8 of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including bovine and porcine
  • blocking peptide, sc-104911 P
 

See additional DOCK 8 Antibodies.

Ordering InformationGene Info
Recommended Support Products:
(click button of application of choice)
WB   IF   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
DOCK 8 Antibody (T-13) sc-104911 200 µg/ml $279
DOCK 8 (T-13) P sc-104911 P
(peptide)
100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
DOCK 8 siRNA (h) sc-92764 10 µM $258
DOCK 8 siRNA (m) sc-143137 10 µM $258
DOCK 8 (h)-PR sc-92764-PR 10 µM, 20 µl $23
DOCK 8 (m)-PR sc-143137-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
DOCK 8 shRNA Plasmid (h) sc-92764-SH 20 µg $520
DOCK 8 shRNA Plasmid (m) sc-143137-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
DOCK 8 shRNA (h) Lentiviral Particles sc-92764-V 200 µl $625
DOCK 8 shRNA (m) Lentiviral Particles sc-143137-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human DOCK8 81704 9p24.3 Q8NF50
611432
Mouse Dock8 76088 19 B Q8C147
N/A
 


DOCK 8 (dedicator of cytokinesis 8) is a 2,099 amino acid protein that contains one DHR-2 (CZH-2) domain and one DHR-1 (CZH-1) domain. One of several members of the DOCK family of cytokinesis-regulating proteins, DOCK 8 functions as a potential guanine nucleotide exchange factor (GEF) that may play a role in protein activation and is thought to influence Actin organization. Defects in the gene encoding DOCK 8 may be associated with the pathogenesis of autosomal dominant mental retardation, possibly due to errors in Actin-based cytoskeletal structure. Multiple isoforms of DOCK 8 exist due to alternative splicing events. The gene encoding DOCK 8 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome.