PACSIN1 Background Information PACSINs are members of a family of cytoplasmic adapter proteins, which share a conserved C-terminal protein binding SH3 domain and a CDC15-NT domain (1,2). PACSIN 1-related proteins include syndapin 1 (the rat homolog of PACSIN 1), FAP52, EM13, and PSTPIP, all of which seem to be involved in signaling pathways associated with cytoskeletal organization (3-6). PACSIN 1 expression is restricted to terminally differentiated neural tissue, whereas PACSIN 2 is widely expressed (1). PACSIN 2 shows vesicle-like distribution and may be involved in regulating endocytotic processes (2).
PACSIN1 (K-17) Product Citations
See how others have used PACSIN1 (K-17): sc-10412 antibody and or PACSIN1 (K-17) antibody conjugates.
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PACSIN1 (K-17)
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PACSIN1 (K-17): sc-10412. Western blot analysis of PACSIN1 expression in rat cerebellum (A) and mouse brain (B) extracts.
PACSIN1 (K-17): sc-10412. Western blot analysis of PACSIN1 expression in non-transfected: sc-117752 (A) and human PACSIN1 transfected: sc-114474 (B) 293T whole cell lysates.