VGF Background Information Nerve growth factor (NGF) is a peptide that plays a key role in the differentiation and survival of neurons in the peripheral nervous system (PNS) and the central nervous system (CNS). VGF is a peptide synthesized and secreted by neurons and is upregulated by NGF in the PC12 cell line. VGF is widely expressed in both the PNS and CNS, but is especially abundant in the adult hypothalamus. VGF plays an essential role in how the brain regulates energy expenditure and body weight. Its expression is rapidly induced by injury, the circadian clock, and neuronal activity.
VGF (D-20) Product Citations
See how others have used VGF (D-20): sc-10381 antibody and or VGF (D-20) antibody conjugates.
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VGF (D-20)
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VGF (D-20): sc-10381. Immunoperoxidase staining of formalin fixed, paraffin-embedded mouse brain tissue showing cytoplasmic and extracellular localization.
Western blot analysis of VGF expression in whole cell lysates prepared from untreated (A,C) and NGF-treated (B,D) PC-12 cells. Antibodies tested include VGF (D-20): sc-10381 (A,B) and VGF (G-17): sc-10380 (C,D).
VGF (D-20): sc-10381. Western blot analysis of VGF expression in NGF-treated PC-12 whole cell lysate.
