Welcome to Santa Cruz Biotechnology!
SCBT Home
Home » Synthesis and Degradation » AOF1 Antibodies » AOF1 Antibody (V-20): sc-103388

AOF1 Antibody (V-20): sc-103388

 |  Datasheet

(Based on data analysis)
  • AOF1 Antibody (V-20) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping within an internal region of AOF1 of human origin
  • recommended for detection of AOF1 of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
  • blocking peptide, sc-103388 P
 

See additional AOF1 Antibodies.

Ordering InformationGene Info
Recommended Support Products:
(click button of application of choice)
WB   IF   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
AOF1 Antibody (V-20) sc-103388 200 µg/ml $279
AOF1 (V-20) P sc-103388 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
AOF1 siRNA (h) sc-95467 10 µM $258
AOF1 siRNA (m) sc-105073 10 µM $258
AOF1 (h)-PR sc-95467-PR 10 µM, 20 µl $23
AOF1 (m)-PR sc-105073-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
AOF1 shRNA Plasmid (h) sc-95467-SH 20 µg $520
AOF1 shRNA Plasmid (m) sc-105073-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
AOF1 shRNA (h) Lentiviral Particles sc-95467-V 200 µl $625
AOF1 shRNA (m) Lentiviral Particles sc-105073-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human AOF1 221656 6p22.3 Q8NB78
 n/a
Mouse Aof1 218214 13 A5 Q8CIG3
 N/A
 

AOF1 (amine-oxidase flavin-containing domain 1), whose alternative names include KDM1B (lysine (K)-specific demethylase 1B) or LSD2 (lysine-specific histone demethylase 2), is an 823 amino acid nuclear protein belonging to the flavin monoamine oxidase family. As a histone demethylase, AOF1 specifically demethylates Lys4 of histone H3, a marker for epigenetic transcriptional activation, by interacting with a long stretch of the H3 N-terminal tail of mono- and dimethylated Lys4. Existing as three alternatively spliced isoforms, AOF1 is required for de novo DNA methylation of some imprinted genes in oocytes and contains a single SWIRM domain that is implicated in chromatin regulation. AOF1 contains one CW-type zinc finger and is encoded by a gene located on human chromosome 6p22.3.