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- rabbit polyclonal IgG, 100µg/ml
- raised against LARP1 of human origin
- recommended for detection of LARP1 of human, rat and canine origin by WB, IP, IF, IHC(P) and ELISA
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Ordering Information
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
LARP1 |
23367 |
5q33.2 |
NM_015315, NM_033551 |
Q6PKG0
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n/a |
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LARP1 Background Information
La-related protein 1 (LARP1), also known as KIAA0731, is a 1,096 amino acid protein belonging to the LARP family. LARP1 contains two conserved regions, one that shares homology with La/SSB proteins and one that is conserved only across LARP family proteins. Within the La/SSB conserved region, LARP1 contains a HTH La-type RNA-binding domain, which may indicate a role in RNA stabalization and folding. Upon DNA damage, LARP1 is phosphorylated by ATR or ATM. LARP1 interacts with many signaling intermediate proteins, including 14-3-3 ∫ , 14-3-3 © , 14-3-3 † and 14-3-3 Ω. Widely expressed, LARP1 levels are highest in heart. LARP1 exists as three isoforms produced by alternative splicing. |
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LARP1 (P-21)
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LARP1 (P-21): sc-102006. Immunoperoxidase staining of formalin fixed, paraffin-embedded human brain tissue showing cytoplasmic staining.
LARP1 (P-21): sc-102006. Western blot analysis of LARP1 expression in Hep G2 whole cell lysate.
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