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p-PKC βI Antibody (Thr 642): sc-101776

 |  Datasheet

(Based on data analysis)

  • p-PKC βI Antibody (Thr 642) is a rabbit polyclonal IgG provided at 100 µg/ml
  • epitope corresponding to phosphorylated Thr 642 of PKC βI of human origin
  • recommended for detection of Thr 642 phosphorylated PKC βI of rat origin, correspondingly phosphorylated Thr 641 of human origin and correspondingly phosphorylated Thr 609 of mouse origin by WB, IP, IF and IHC(P)
  • See 1 citations for p-PKC βI Antibody (Thr 642)
 

See additional PKC Antibodies including PKC, PKC alpha, PKC beta, PKC delta, PKC epsilon, PKC eta, PKC gamma, PKC iota, PKC lambda, PKC mu, PKC nu, PKC theta, PKC zeta and Pkc1.

Also see PKC beta Inhibitors or PKC beta Activators for functional analysis of cellular responses to PKC beta and PKC beta.


Ordering InformationProduct CitationsGene Info
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
p-PKC βI Antibody (Thr 642) sc-101776 100 µg/ml $279
Lambda Phosphatase sc-200312 100000 units in 0.25 ml $462
Lambda Phosphatase sc-200312A 20000 units in 0.05 ml $116
Lambda Phosphatase sc-200312 100000 units in 0.25 ml $462
Lambda Phosphatase sc-200312A 20000 units in 0.05 ml $116
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
PKC β siRNA (h) sc-29450 10 µM $258
PKC β siRNA (m) sc-36255 10 µM $258
PKC β (h)-PR sc-29450-PR 10 µM, 20 µl $23
PKC β (m)-PR sc-36255-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
PKC β shRNA Plasmid (h) sc-29450-SH 20 µg $520
PKC β shRNA Plasmid (m) sc-36255-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
PKC β shRNA (h) Lentiviral Particles sc-29450-V 200 µl $625
PKC β shRNA (m) Lentiviral Particles sc-36255-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
K-562 + PMA Cell Lysate sc-2280 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human PRKCB1 5579 16p12.1 NM_002738, NM_212535 P05771
 176970
Mouse Prkcb1 18751 7 F3 P68404
 N/A
 

Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes including conventional (c) PKC isoforms (å, ∫I, ∫II and ©) and novel (n) PKC isoforms (∂, é, Ω, ñ and †). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of nPKC ∂ and é are independent of Ca2+. On the other hand, nPKC ∂ and é, as well as all of the cPKC members, possess phorbol ester-binding activities and kinase activities.

p-PKC βI Antibody (Thr 642) Product Citations
See how others have used p-PKC βI Antibody (Thr 642) and or p-PKC βI Antibody (Thr 642) conjugates.


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p-PKC βI Antibody (Thr 642) Data
Click on image to enlarge
sc-101776
p-PKC βI (Thr 642): sc-101776. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human lung carcinoma tissue showing cytoplasmic staining.
sc-101776
p-PKC βI (Thr 642): sc-101776. Western blot analysis of phosphorylated PKC βI expression in untreated (A) and PMA-treated (B) K-562 whole cell lysates.
sc-101776
p-PKC βI (Thr 642): sc-101776. Western blot analysis of PKC βI phosphorylation in untreated (A), nocodazole treated (B) and lambda protein phosphatase (sc-200312A) and nocodazole treated (C) K-562 whole cell lysates.
sc-101776
Western blot analysis of PKC βI phosphorylation in untreated (A, D), PMA treated (B, E) and PMA and lambda protein phosphatase treated (C, F) K-562 whole cell lysates. Antibodies tested include p-PKC βI (Thr 642): sc-101776 (A, B, C) and PKC βI (E-3): sc-8049 (D, E, F).
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