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p-c-Jun Antibody (Ser 243): sc-101719

 |  Datasheet

(Based on data analysis)

  • p-c-Jun Antibody (Ser 243) is a rabbit polyclonal IgG provided at 100 µg/ml
  • epitope corresponding to phosphorylated Ser 243 of c-Jun of human origin
  • recommended for detection of Ser 243 phosphorylated c-Jun of human origin and correspondingly phosphorylated Ser 246 of mouse and rat orign by WB, IP, IF and IHC(P)
  • See 1 citations for p-c-Jun Antibody (Ser 243)
 

See additional Jun Antibodies including Jun, c-Jun, Jun B and Jun D.

Also see c-Jun Activators for functional analysis of cellular responses to c-Jun.


Ordering InformationProduct CitationsGene Info
Recommended Support Products:
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WB   IP   IF   IHC(P)   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
p-c-Jun Antibody (Ser 243) sc-101719 100 µg/ml $279
Lambda Phosphatase sc-200312 100000 units in 0.25 ml $462
Lambda Phosphatase sc-200312A 20000 units in 0.05 ml $116
Lambda Phosphatase sc-200312 100000 units in 0.25 ml $462
Lambda Phosphatase sc-200312A 20000 units in 0.05 ml $116
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
c-Jun siRNA (h) sc-29223 10 µM $258
c-Jun siRNA (m) sc-29224 10 µM $258
c-Jun (h)-PR sc-29223-PR 10 µM, 20 µl $23
c-Jun (m)-PR sc-29224-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
c-Jun shRNA Plasmid (h) sc-29223-SH 20 µg $520
c-Jun shRNA Plasmid (m) sc-29224-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
c-Jun shRNA (h) Lentiviral Particles sc-29223-V 200 µl $625
c-Jun shRNA (m) Lentiviral Particles sc-29224-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
A-431 nuclear extract sc-2122 250 µg/0.05 ml $143
HeLa + UV Cell Lysate sc-2221 500 µg/200 µl $104
c-Jun (m): 293T Lysate sc-125069 100 µg/200 µl $205
NIH/3T3 + anisomycin Cell Lysate sc-2247 500 µg/200 µl $104
NIH/3T3 Whole Cell Lysate sc-2210 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human JUN 3725 1p32.1 NM_002228 P05412
 165160
Mouse Jun 16476 4 C5 P05627
 N/A
 

Genes belonging to the Jun and Fos oncogene families encode nuclear proteins that are found to be associated with a number of transcriptional complexes (1,2). The c-Jun protein is a major component of the transcription factor AP-1 (3,4), originally shown to mediate phorbol ester tumor promoter (TPA)-induced expression of responsive genes through the TPA-response element (TRE) (3,4). The Jun proteins form homo- and heterodimers which bind the TRE, but the Fos proteins are active only as heterodimers with any of the Jun proteins (5,6). Fos/Jun heterodimers have a much higher affinity for the TRE than Jun homodimers. Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain (7). An inhibitor of Fos/Jun function, termed IP-1, associates with Fos and Jun and is deactivated upon phosphorylation induced by the cAMP-dependent protein kinase A (PKA) (8).

p-c-Jun Antibody (Ser 243) Product Citations
See how others have used p-c-Jun Antibody (Ser 243) and or p-c-Jun Antibody (Ser 243) conjugates.


1 total citations
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p-c-Jun Antibody (Ser 243) Data
Click on image to enlarge
sc-101719
p-c-Jun (Ser 243): sc-101719. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human breast carcinoma tissue showing nuclear localization.
sc-101719
p-c-Jun (Ser 243): sc-101719. Western blot analysis of phosphorylated c-Jun expression in untreated (A) and UV-treated (B) HeLa whole cell lysates.
sc-101719
Western blot analysis of c-Jun phosphorylation in non-transfected: sc-117752 (A, D), untreated mouse c-Jun transfected: sc-125069 (B, E) and lambda protein phosphatase treated mouse c-Jun transfected: sc-125069 (C, F) 293T whole cell lysates. Antibodies tested include p-c-Jun (Ser 243): sc-101719 (A, B, C) and c-Jun (N): sc-45 (D, E, F).
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