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home » Transcription Regulators » Histone Antibody / Histone Antibodies » p-Histone H2A.X (Ser 139): sc-101696

p-Histone H2A.X (Ser 139) Antibody: sc-101696

  |  Datasheet
  • rabbit polyclonal IgG, 100 µg/ml
  • epitope corresponding to phosphorylated Ser 139 of Histone H2A.X of human origin
  • recommended for detection of Ser 139 phosphorylated Histone H2A.X of human and mouse origin and correspondingly phosphorylated Ser 140 of rat origin by WB and IP
 
Additional Histone Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human H2AFX 3014 11q23.3 NM_002105 P16104
 601772
Mouse H2afx 15270 9 A5.2 P27661
 N/A
Mouse H2afx 15270 9 A5.2 P27661
 N/A
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
p-Histone H2A.X (Ser 139) sc-101696 100 µg/ml $279
Lambda Phosphatase sc-200312 100,000 units $462
Lambda Phosphatase sc-200312A 20,000 units $116
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Histone H2A.X siRNA (h) sc-62464 10 µM $258
Histone H2A.X siRNA (m) sc-62465 10 µM $258
Histone H2A.X (h)-PR sc-62464-PR 10 µM $23
Histone H2A.X (m)-PR sc-62465-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Histone H2A.X shRNA Plasmid (h) sc-62464-SH 20 µg $520
Histone H2A.X shRNA Plasmid (m) sc-62465-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Histone H2A.X shRNA (h) Lentiviral Particles sc-62464-V 200 µl $625
Histone H2A.X shRNA (m) Lentiviral Particles sc-62465-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Histone H2A.X (m): 293T Lysate sc-120804 100µg/200µl $205

p-Histone H2A.X Background Information
Histone H2A.X is a member of the Histone H2A family, which is involved in nucleosomal organization of chromatin. The H2AFX gene is located in close proximity to the Porphobilinogen deaminase (PBG-D) gene in both mouse and human, and maps to chromosome 9 and 11q23, respectively. H2A.X differs from the other members of the H2A family by the presence of a highly conserved C-terminal motif. It is rapidly phosphorylated in response to ionizing radiation and plays an important role in the recognition and repair of DNA double stranded breaks. The phosphorylated form of H2A.X, designated ©-H2A.X, forms nuclear foci at the heavy chain constant region of cells involved in class switch recombination (CSR), a region-specific DNA reaction that replaces one immunoglobulin heavy chain constant region gene with another. The phosphorylated ©-H2A.X is also thought to initiate subsequent repair factors, including Rad50, Rad51 and BRCA1.

p-Histone H2A.X (Ser 139) Product Citations
See how others have used p-Histone H2A.X (Ser 139): sc-101696 antibody and or p-Histone H2A.X (Ser 139) antibody conjugates.


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p-Histone H2A.X (Ser 139)
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sc-101696
p-Histone H2A.X (Ser 139): sc-101696. Western blot analysis of phosphorylated Histone H2A.X expression in untreated (A) and UV-treated (B) 293 whole cell lysates.
sc-101696
p-Histone H2A.X (Ser 139): sc-101696. Western blot analysis of Histone H2A.X phosphorylation in non-transfected: sc-117752 (A), untreated mouse Histone H2A.X transfected: sc-120804 (B) and lambda protein phosphatase treated mouse Histone H2A.X transfected: sc-120804 (C) 293T whole cell lysates.
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