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p-HDAC4 Antibody (Ser 632): sc-101691

 |  Datasheet

(Based on data analysis)

  • p-HDAC4 Antibody (Ser 632) is a rabbit polyclonal IgG provided at 100 µg/ml
  • epitope corresponding to phosphorylated Ser 632 of HDAC4 of human origin
  • recommended for detection of Ser 632 phosphorylated HDAC4 of human origin, correspondingly phosphorylated Ser 629 of mouse origin and correspondingly phosphorylated Ser 631 of rat origin by WB and IP
 

See additional HDAC Antibodies including HDAC, HDAC1, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9, HDAC10 and HDAC11.

Also see HDAC4 Inhibitors for functional analysis of cellular responses to HDAC4.


Ordering InformationGene Info
Recommended Support Products:
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WB   IP   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
p-HDAC4 Antibody (Ser 632) sc-101691 100 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
HDAC4 siRNA (h) sc-35540 10 µM $258
HDAC4 siRNA (m) sc-35541 10 µM $258
HDAC4 (h)-PR sc-35540-PR 10 µM, 20 µl $23
HDAC4 (m)-PR sc-35541-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
HDAC4 shRNA Plasmid (h) sc-35540-SH 20 µg $520
HDAC4 shRNA Plasmid (m) sc-35541-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
HDAC4 shRNA (h) Lentiviral Particles sc-35540-V 200 µl $625
HDAC4 shRNA (m) Lentiviral Particles sc-35541-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Jurkat + Calyculin A Cell Lysate sc-2277 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human HDAC4 9759 2q37.3 NM_006037, XM_001126419 P56524
 605314
Mouse Hdac4 208727 1 D Q6NZM9
 N/A
 

In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acet-ylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, p300/CBP, PCAF (p300/CBP-associated factor), HAT1 and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1), HDAC2 (also designated RPD3) and HDAC3-6 have been identified as histone deacetylases.
p-HDAC4 Antibody (Ser 632) Data
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sc-101691
p-HDAC4 (Ser 632): sc-101691. Western blot analysis of phosphorylated HDAC4 expression in untreated (A) and Calculin A-treated (B) Jurkat whole cell lysates.
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