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p-VASP Antibody (5C6): sc-101440

 |  Datasheet

(Based on data analysis)

  • p-VASP Antibody (5C6) is a mouse monoclonal IgG1 provided at 50 µg/0.5 ml
  • raised against synthetic VASP of human origin, phosphorylated at serine 157
  • recommended for detection of Ser 157 phosphorylated VASP of mouse and human origin by WB, IP, IF, FCM and ELISA
 

See additional VASP Antibodies.

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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
p-VASP Antibody (5C6) sc-101440 50 µg/0.5 ml $279
Lambda Phosphatase sc-200312 100000 units in 0.25 ml $462
Lambda Phosphatase sc-200312A 20000 units in 0.05 ml $116
Lambda Phosphatase sc-200312 100000 units in 0.25 ml $462
Lambda Phosphatase sc-200312A 20000 units in 0.05 ml $116
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
VASP (h): 293T Lysate sc-114829 100 µg/200 µl $205
NIH/3T3 + forskolin Cell Lysate sc-24741 500 µg/200 µl $104
VASP (m): 293T Lysate sc-127758 100 µg/200 µl $205
VASP (m2): 293T Lysate sc-127759 100 µg/200 µl $205
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human VASP 7408 19q13.32 NM_001008736, NM_003370 P50552
 601703
Mouse Vasp 22323 7 A3 P70460
 N/A
 

The Wiskott-Aldrich syndrome (WAS) is characterized by thrombocytopenia, eczema, defects in cell-mediated and humoral immunity and a propensity for lymphoproliferative diseases. The syndrome is the result of a mutation in the gene encoding a proline-rich protein termed WASP. A distantly related protein, VASP (vasodilator-stimulated phosphoprotein), is involved in the maintenance of cytoarchitecture by interacting with actin-like filaments. VASP shares a limited degree of homology with the amino terminus of WASP, which is frequently mutated in WAS patients. An established substrate of cAMP and cGMP dependent kinases, VASP is phosphorylated on a regulatory serine residue 157 and localizes to focal adhesions, microfilaments and highly active regions of the plasma membrane. VASP is also phosphorylated on serine 239 by cGMP-dependent protein kinase.
p-VASP Antibody (5C6) Data
Click on image to enlarge
sc-101440
p-VASP (5C6): sc-101440. Western blot analysis of VASP phosphorylation expression in non-transfected: sc-117752 (A) and human VASP transfected: sc-114829 (B) 293T whole cell lysates.
sc-101440
p-VASP (5C6): sc-101440. Western blot analysis of VASP phosphorylation in non-transfected: sc-117752 (A) and mouse VASP transfected: sc-127758 (B) 293T whole cell lysates.
sc-101440
p-VASP (5C6): sc-101440. Western blot analysis of VASP phosphorylation in untreated non-transfected: sc-117752 (A), untreated human VASP transfected: sc-114829 (B) and lambda protein phosphatase treated human VASP transfected: sc-114829 (C) 293T whole cell lysates.
sc-101440
p-VASP (5C6): sc-101440. Western blot analysis of VASP phosphorylation in untreated (A) and lambda protein phosphatase treated (B) human platelet whole cell lysates.
sc-101440
p-VASP (5C6): sc-101440. Western blot analysis of VASP phosphorylation in non-transfected: sc-117752 (A) and mouse VASP transfected: sc-127759 (B) 293T whole cell lysates.
sc-101440
Western blot analysis of VASP phosphorylation in non-transfected: sc-117752 (A, D), untreated human VASP transfected: sc-114829 (B, E) and lambda protein phosphatase treated human VASP transfected: sc-114829 (C, F) 293T whole cell lysates. Antibodies tested include p-VASP (5C6): sc-101440 (A, B, C) and VASP (A-11): sc-46668 (D, E, F).
sc-101440
Western blot analysis of VASP phosphorylation in untreated (A, C), and lambda protein phosphatase treated (B, D) human platelet whole cell lysate. Antibodies tested include p-VASP (5C6): sc-101440 (A, B) and VASP (A-11): sc-46668 (C, D).
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