p-VASP Antibody (16C2): sc-101439
- p-VASP Antibody (16C2) is a mouse monoclonal IgG1, cited in 10 publications, provided at 50 µg/0.5 ml
- raised against synthetic VASP of human origin, phosphorylated at serine 239
- recommended for detection of Ser 239 phosphorylated VASP of mouse, rat and human origin by WB, IP, IF, FCM and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for p-VASP Antibody (16C2). This work is in progress.
QUICK LINKS
SEE ALSO...
p-VASP Antibody (16C2) is a mouse monoclonal IgG1 antibody that detects VASP in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). anti-VASP antibody (16C2) specifically recognizes the phosphorylated form of VASP, which plays a crucial role in the regulation of actin dynamics and cellular architecture. VASP is primarily located in focal adhesions and microfilaments, where VASP interacts with actin filaments to facilitate cellular processes such as migration and adhesion. VASP localization is vital for maintaining the structural integrity of cells and enabling them to respond effectively to external stimuli. Additionally, VASP undergoes post-translational modifications, including phosphorylation at serine residues, which modulate VASP activity and interactions with other proteins. These modifications are essential for the proper functioning of VASP in signaling pathways that govern cytoskeletal rearrangements, making VASP a key player in various physiological and pathological processes. VASP monoclonal antibody (16C2) detection of phosphorylated VASP allows researchers to study VASP role in cellular signaling and implications in diseases such as cancer and cardiovascular disorders.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
p-VASP Antibody (16C2) References:
- Neutrophil-derived glutamate regulates vascular endothelial barrier function. | Collard, CD., et al. 2002. J Biol Chem. 277: 14801-11. PMID: 11847215
- Association of VASP with TRPC4 in PKG-mediated inhibition of the store-operated calcium response in mesangial cells. | Wang, X., et al. 2007. Am J Physiol Renal Physiol. 293: F1768-76. PMID: 17913834
- Variations in Intraplatelet Phospho-VASP Expression Due to Pre-analytical Sample Preparations, Illustration of a Quality Control Issue in Platelet Pharmacology. | Gharehbaghian, A., et al. 2015. Iran J Pharm Res. 14: 321-8. PMID: 25561938
- PDE3A mutations cause autosomal dominant hypertension with brachydactyly. | Maass, PG., et al. 2015. Nat Genet. 47: 647-53. PMID: 25961942
- Vasodilator-Stimulated Phosphoprotein Activity Is Required for Coxiella burnetii Growth in Human Macrophages. | Colonne, PM., et al. 2016. PLoS Pathog. 12: e1005915. PMID: 27711191
- Vasodilator-stimulated phosphoprotein (VASP) is not a major mediator of platelet aggregation, thrombogenesis, haemostasis, and antiplatelet effect of prasugrel in rats. | Ito, Y., et al. 2018. Sci Rep. 8: 9955. PMID: 29967338
- Abnormal cGMP-dependent protein kinase I-mediated decidualization in preeclampsia. | Chen, J., et al. 2021. Hypertens Res. 44: 318-324. PMID: 33093639
- A new function for MAP4K4 inhibitors during platelet aggregation and platelet-mediated clot retraction. | Nam, GS., et al. 2021. Biochem Pharmacol. 188: 114519. PMID: 33737052
- Improved Endothelium-Dependent Relaxation of Thoracic Aorta in Niclosamide-Treated Diabetic Rats. | Engin, S., et al. 2021. Cardiovasc Toxicol. 21: 563-571. PMID: 33772737
- Anti-Thrombotic Effects of Artesunate through Regulation of cAMP and PI3K/MAPK Pathway on Human Platelets. | Yoon, SS., et al. 2022. Int J Mol Sci. 23: PMID: 35163507
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p-VASP Antibody (16C2) | sc-101439 | 50 µg/0.5 ml | $316.00 |