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home » Transcription Regulators » TSC-22 Antibody / TSC-22 Antibodies » TSC-22 D4 (JJ-2): sc-101193

TSC-22 D4 (JJ-2) Antibody: sc-101193

  |  Datasheet
  • mouse monoclonal IgG1, 100 µg/ml
  • raised against recombinant TSC-22 D4 of human origin
  • recommended for detection of TSC-22 D4 of human origin by WB, IP and ELISA
 
Additional TSC-22 Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IP   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human TSC22D4 81628 7q22.1 NM_030935 Q9Y3Q8
 n/a
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
TSC-22 D4 (JJ-2) sc-101193 100 µg/ml $295
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
TSC-22 D4 siRNA (h) sc-63173 10 µM $258
TSC-22 D4 (h)-PR sc-63173-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
TSC-22 D4 shRNA Plasmid (h) sc-63173-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
TSC-22 D4 shRNA (h) Lentiviral Particles sc-63173-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
TSC-22 D4 (h): 293T Lysate sc-114517 100µg/200µl $205
K-562 Whole Cell Lysate sc-2203 500 µg/200 µl $104

TSC-22 D4 Background Information
Transforming growth factor-beta-stimulated clone-22 (TSC-22) acts as a transcriptional regulator to modulate cell growth and differentiation, as well as cell death. TSC-22 contains a leucine zipper domain as well as a nuclear export signal, resulting in cytoplasmic localization in living cells. However, concomitant with the induction of apoptosis, TSC-22 translocates from the cytoplasm to the nucleus and shows transcriptional regulatory activity. TSC-22 acts as a major downstream component in both the TGF-beta pathway and the PPAR© signaling pathway. The association of these two pathways with tumor suppression, and the significant downregulation of TSC-22 mRNA in various cancer types, implies an antiproliferative role for TSC-22. TSC-22 D4 (TSC22 domain family protein 4), also known as TILZ2 or THG-1 is a 395 amino acid protein that is related to TSC-22 and functions as a transcriptional repressor.
TSC-22 D4 (JJ-2)
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sc-101193
TSC-22 D4 (JJ-2): sc-101193. Western blot analysis of TSC-22 D4 expression in non-transfected: sc-117752 (A) and human TSC-22 D4 transfected: sc-114517 (B) 293T whole cell lysates.
sc-101193
TSC-22 D4 (JJ-2): sc-101193. Western blot analysis of TSC-22 D4 expression in K-562 whole cell lysate.
sc-101193
TSC-22 D4 (JJ-2): sc-101193. Western blot analysis of TSC-22 D4 expression in K-562 whole cell lysate.
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