SLMAP Background Information SLMAP (sarcolemmal membrane-associated protein) is a 828 amino acid single-pass type IV membrane protein. Localized to the sacrcolemma in non-replicating cells, SLMAP relocates to centrosomes in a microtubule-dependent manner during cleavage in muscle tissues. SLMAP is thought to be involved in protein-protein interactions, as well as play a role in myoblast fusion. As a homodimeric integral membrane protein, SLMAP has two leucine zippers which form a 77 amino acid coiled-coil structure and contains one forkhead-associated (FHA) domain. Coiled- coil structures may be important for the regulation of neurotransmitter release, N-type calcium channels and membrane fusion, while FHA domains are involved in nuclear signaling. SLMAP exists as eight isoforms produced by alternative splicing.
SLMAP (SJ-09)
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SLMAP (SJ-09): sc-100957. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human testis tissue showing membrane and cytoplasmic localization.
SLMAP (SJ-09): sc-100957. Western blot analysis of SLMAP expression in HeLa whole cell lysate.
